Detection method of gingko flavonol glycosides

A detection method and technology of flavonol glycosides, which are applied in the direction of measuring devices, instruments, scientific instruments, etc., can solve problems such as the inability to guarantee the efficacy of preparations and the inability to use quality control to control the quality of finished products
CN112697899AActive Publication Date: 2021-04-23CHINA PHARM UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CHINA PHARM UNIV
Publication Date
2021-04-23

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Abstract

The invention discloses a detection method of gingko flavonol glycosides. The detection method comprises the following steps of: (1) preparing reference substances and a test solution, the reference substances being rutin, hyperoside, isoquercitrin, quercetin-3-O-2''-glucose rhamnoside, kaempferol-3-O-beta-D-rutinoside, narcissoside, syringetin-3-O-beta-D-rutinoside, cosmosiin, quercetin-3-O-p-coumaroyl rhamnose glucoside and kaempferol-3-O-p-coumaroyl rhamnose glucoside reference substances; (2) performing detection; (3) establishing a standard fingerprint spectrum; and (4) calculating the content of common peaks in the fingerprint spectrum established in the step (3). According to the detection method, a specific standard fingerprint spectrum of the ginkgo flavonol glycosides is established, the content of main flavonol glycosides in gingko and related extracts and pharmaceutical preparations thereof can be accurately detected, and the accuracy, precision, reproducibility and stability are good.
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Description

technical field

[0001] The invention relates to a detection method of ginkgo flavonol glycosides, in particular to a detection method of ginkgo flavonol glycosides which can accurately detect the contents of main flavonoid glycosides in ginkgo and related extracts and pharmaceutical preparations. Background technique

[0002] Ginkgo biloba is the dry leaf of Ginkgo biloba L. The cultivation area extends from Liaoning in the north, to Guangdong in the south, from Zhejiang in the east, to Shaanxi and Gansu in the west, and to Sichuan, Guizhou, and Yunnan in the southwest. It can be used for symptoms such as blood stasis blocking collaterals, chest pain and heartache. Its extract has various pharmacological effects such as improving cardiovascular and cerebrovascular circulation, protecting the heart, antagonizing PAF, and eliminating free radicals, and is often used to prevent and treat cardiovascular and cerebrovascular diseases. There are many pharmacologically active ingr...

Claims

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