Fermented traditional Chinese medicine immunopotentiator, and preparation method and application thereof

An immune enhancer and traditional Chinese medicine technology, applied in biochemical equipment and methods, applications, pharmaceutical formulations, etc., can solve problems affecting the healthy development of animal husbandry, endangering public health safety, animal intestinal flora imbalance, etc. degree and diversity, low toxicity and side effects, and the effect of increasing polysaccharide content

Pending Publication Date: 2021-04-27
HENAN AGRICULTURAL UNIVERSITY +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, while antibiotics kill pathogenic bacteria, they can also lead to problems such as drug residues, bacterial resistance, and intestinal flora imbalance in animals, which seriously affect the healthy development of animal husbandry and endanger public health safety.

Method used

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  • Fermented traditional Chinese medicine immunopotentiator, and preparation method and application thereof
  • Fermented traditional Chinese medicine immunopotentiator, and preparation method and application thereof
  • Fermented traditional Chinese medicine immunopotentiator, and preparation method and application thereof

Examples

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Effect test

preparation example Construction

[0019] The present invention provides the preparation method of the fermented traditional Chinese medicine immunopotentiator described in the above technical scheme, comprising the following steps: carrying out water extraction of Radix Radix Radix and Radix Astragali to obtain a water extract, mixing the water extract with LB basal medium to obtain Fermentation medium: inoculating fermenting bacteria into the fermentation medium for fermentation to obtain a fermented traditional Chinese medicine immune enhancer.

[0020] In the invention, the Radix Radix Radix and Radix Astragalus are subjected to water extraction to obtain water extracts. In the present invention, the water extraction preferably includes the following steps: soaking Astragalus and Radix Radix Radix in water, decocting, filtering and concentrating the filtrate to obtain a water extract. In the present invention, the mass ratio of Astragalus and Radix Radix is ​​preferably (1-5):1, more preferably 1:2; Prefer...

Embodiment 1

[0027] A fermented traditional Chinese medicine immune enhancer, the preparation method is as follows:

[0028] 1) Preparation of Radix Radix Radix and Radix Astragalus Water Extract

[0029] Accurately weigh 1000g of astragalus decoction pieces and 1000g of isatis root decoction pieces with a balance; mix astragalus and isatidis root, add water to soak, wherein the volume ratio of the total mass of astragalus and isatidis root to water is 1g / 5mL, soak for 30min, and decoct at 100°C For 40 minutes, filter the medicinal liquid with gauze, add the same volume of distilled water as the soaking process to the medicinal residue and continue to decoct for 40 minutes, repeat the decoction 3 times; put the medicinal liquid obtained after 3 decoctions through gauze filtration into a rotary evaporator, Concentrate the medicinal liquid to contain crude drug 1g / mL, and obtain the water extract of Radix Radix Radix and Radix Astragali after high-pressure sterilization.

[0030] 2) ferment...

Embodiment 2

[0033]A fermented traditional Chinese medicine immunopotentiator, the preparation method of which is the same as in Example 1, except that the fermentation temperature is 30°C and the fermentation time is 48 hours.

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Abstract

The invention provides a fermented traditional Chinese medicine immunopotentiator, and belongs to the technical field of feed additives. The fermented traditional Chinese medicine immunopotentiator provided by the invention is obtained in a way that fermentation is carried out after radix isatidis and radix astragali are subjected to water extraction. In the fermented traditional Chinese medicine immunopotentiator, the radix isatidis and the radix astragali are subjected to the water extraction and the fermentation, and the fermented traditional Chinese medicine improves the content of the effective ingredients of the medicine and also contains probiotics beneficial for the health of animals. A result of the embodiment indicates that the traditional Chinese medicine immunopotentiator provided by the invention obviously improves the content of polysaccharides in the medicine, after the fermented traditional Chinese medicine immunopotentiator disclosed by the invention feeds a weaning lamb, the abundance and the diversity of lamb intestinal flora are improved, the immunity of the weaning lamb is obviously improved, the natural infection rate of Sphaerozoum fuscum is lowered, Ovis aries can be accelerated to grow, a daily gain is improved, and a feed and weight ratio is lowered.

Description

technical field [0001] The invention belongs to the technical field of feed additives, and in particular relates to a fermented traditional Chinese medicine immune enhancer and its preparation method and application. Background technique [0002] Weaning lambs will have a variety of stress reactions. Weaning lambs at this stage often show low immunity and are susceptible to various pathogens. Antibiotics are commonly used clinically for prevention. However, while antibiotics kill pathogenic bacteria, they can also lead to problems such as drug residues, bacterial resistance, and animal intestinal flora imbalance, which seriously affect the healthy development of animal husbandry and endanger public health safety. More and more countries prohibit the use of antibiotic products as animal growth promoters, and my country has also promulgated a series of laws and regulations to prohibit the use of growth-promoting antibiotics in feed. Therefore, it is imminent to develop new an...

Claims

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Application Information

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IPC IPC(8): A23K10/12A23K10/30A23K50/10A23K50/60A61K36/481A61P37/04C12N1/20C12R1/125
CPCA23K10/12A23K10/30A23K50/10A23K50/60A61K36/195A61K36/315A61K36/481A61P37/04C12N1/20A61K2236/19A61K2236/331A61K2236/39A61K2300/00
Inventor 张红英姚春晓宁晓冬杨明凡常娟张英杰刘月琴郭云霞
Owner HENAN AGRICULTURAL UNIVERSITY
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