Nano resveratrol-coated compound as well as preparation method and application thereof

Abstract

The invention belongs to the field of a nanotechnology, and provides a nano resveratrol-coated compound as well as a preparation method and application thereof. The preparation method of the nano resveratrol-coated compound comprises the following steps of (1) mixing a lecithin solution and a resveratrol solution to obtain a first mixed solution; (2) adding the first mixed solution into water to obtain a second mixed solution; and (3) purifying the second mixed solution to obtain the nano resveratrol-coated compound. After resveratrol coats lecithin nanoparticles, the effect of continuously and slowly releasing antioxidant components and the good effect of promoting transdermal permeation of antioxidants are achieved, the residence time of the resveratrol in the acting skin part is prolonged, and the bioavailability of the resveratrol is improved.

Description

technical field

[0001] The invention relates to the field of nanotechnology, in particular to a nano-encapsulated resveratrol compound and its preparation method and application. Background technique

[0002] Resveratrol (RSV), also known as stilberol, is a natural polyphenolic flavonoid compound that can be found in the seeds and skins of grapes (red wine), mulberries, peanuts, rhubarb, etc. Resveratrol It has anti-oxidation and anti-free radical effects. Resveratrol contains cis and trans isomers, the latter being considered to be biologically active and most abundant. Resveratrol as a natural antioxidant, the most prominent role is to scavenge free radicals or inhibit the formation of free radicals, delay the aging process of skin cells, inhibit lipid peroxidation and inhibit the activity of tyrosinase, and reduce the formation of melanin , to achieve whitening, blemish, moisturizing and other skin care effects. After intravenous administration, resveratrol is rapidly ...

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