Novel medicine-loadable 3D printing amniotic goggles

Abstract

The invention relates to an ophthalmic treatment appliance. The invention aims to provide a novel medicine-loading 3D printing amniotic membrane mirror. The amniotic membrane mirror has the characteristics of large medicine loading capacity, no need of invasive operation and good treatment effect. According to the technical scheme, the novel medicine-loading 3D printing amniotic membrane mirror is characterized by comprising an amniotic membrane piece, an upper ring and a lower ring, wherein the upper ring and the lower ring are used for clamping, riveting and fixing the amniotic membrane piece after being overlapped up and down; tacrolimus liposome thin layers are respectively prepared on the surfaces of the upper ring and the lower ring; the axial projection of the upper ring and the axial projection of the lower ring are the same elliptical ring, the inner ellipse in the middle of the elliptical ring is a through hole, and the other parts of the elliptical ring are cambered surfaces matched with the ocular surface; and the amniotic membrane sheet is flattened and fixed on the amniotic membrane mirror and shields the whole through hole.

Description

technical field [0001] The invention relates to an ophthalmic treatment device, in particular to a novel drug-loadable 3D printed amniotic mirror. Background technique [0002] For eye diseases (such as ocular surface thermal burn / chemical injury, severe dry eye, etc.), the conventional treatment methods are: [0003] 1. Drug treatment: use glucocorticoids, anti-inflammatory drugs, anti-VEGF drugs, immunosuppressants, tyrosine kinase inhibitors and other drugs for treatment. Currently commonly used drug treatments such as glucocorticoids cannot be used for a long time, as they will cause increased intraocular pressure, cataracts and other problems. Anti-vascular endothelial growth factor also has the problems of corneal epithelial nonunion and high price in the later stage of treatment. Moreover, eye diseases often require frequent use of eye drops and a combination of multiple drugs for treatment, and the therapeutic effect depends on the patient's compliance. [0004] 2...

AI Technical Summary

Problems solved by technology

[0004] 2. Amniotic membrane transplantation: The traditional amniotic membrane transplantation cover requires the use of sutures. It is an invasive operation and requires high equipment. It is prone to complications such as intraoperative pain, bleeding, and amniotic membrane slippage, as well as suture reactions and iatrogenic injuries. And other issues

[0005] 3. Amniotic membrane fixing ring: it can only fix the amniotic membrane, and does not have the function of drug sustained-release carrier. Frequent use of eye drops during treatment will still lead to problems such as poor patient compliance

[0006] 4. Surgical treatment: large trauma, high cost of treatment, poor patient tolerance, etc.

Images