Unlock instant, AI-driven research and patent intelligence for your innovation.

Patch for preventing hand-foot syndrome

A syndrome and patch technology, applied in the directions of heating appliances for therapeutic treatment, cooling appliances for therapeutic treatment, sheet conveying, etc., can solve problems such as the inability to effectively control the temperature adjustment of cold therapy

Active Publication Date: 2021-05-28
TIANJIN TUMOR HOSPITAL
View PDF9 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, when the temperature regulation of cold therapy cannot be effectively controlled, it is easy to produce the opposite effect to the physiological effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Patch for preventing hand-foot syndrome
  • Patch for preventing hand-foot syndrome

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] A patch for preventing hand-foot syndrome, comprising a backing layer, a gel layer and a protective film arranged in sequence, and the components and mass percentages of the gel layer are:

[0039] Polyvinyl alcohol 20-30%,

[0040] Sorbitol 2-5%,

[0041] Calcium carbonate 0.5-1%,

[0042] Pentaerythritol tetraglycidyl ether 0.3-0.5%,

[0043] Hydroxyl-containing water-absorbing resin 3-8%,

[0044] Amino acid 0.02-0.05%,

[0045] Hydroxypropyl methylcellulose 2-4%,

[0046] Nano Fe 2 o 3 1-2%,

[0047] Chinese medicine composition extract 3-5%,

[0048] Vitamin B6 0.05~0.1%,

[0049] The balance is water.

[0050] Preparation:

[0051] 1) Add polyvinyl alcohol to water and stir evenly, and dissolve in a water bath at 80-90°C to obtain an aqueous solution of polyvinyl alcohol;

[0052] 2) Add the remaining components to the above polyvinyl alcohol aqueous solution, stir evenly and place in a water bath at 25°C for crosslinking for 24 hours;

[0053] 3) Af...

Embodiment 2

[0058] The method of embodiment 1 is repeated by the content of each component specified in the following table 1, but with nanometer Al 2 o 3 Substitute Nano Fe 2 o 3 , the test results are listed in Table 1.

Embodiment 3

[0060] The method of embodiment 1 is repeated by the content of each component specified in the following table 1, but with nanometer SiO 2 Substitute Nano Fe 2 o 3 , the test results are listed in Table 1.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a patch for preventing hand-foot syndrome, which comprises a backing layer, a gel layer and a protective film which are arranged in sequence, wherein the gel layer is prepared from the following components in percentage by mass: 20 to 30 percent of polyvinyl alcohol, 2 to 5 percent of sorbitol, 0.5 to 1 percent of calcium carbonate, 0.3 to 0.5 percent of pentaerythritol tetraglycidyl ether, 3 to 8 percent of water-absorbent resin, 0.02 to 0.05 percent of amino acid, 2 to 4 percent of hydroxypropyl methyl cellulose, 1 to 2 percent of nano material, 3 to 5 percent of traditional Chinese medicine composition extracting solution, 0.05 to 0.1 percent of vitamin B6 and the balance of water. According to the invention, by means of the gel layer, the temperature can be controlled to be 21-26 DEG C for 5 h, and the use requirement that the medium low temperature (21-27 DEG C) is kept within the injection time of 2-3 h is met.

Description

technical field [0001] The invention belongs to the field of medical devices, and relates to hand-foot syndrome prevention technology, in particular to a patch for preventing hand-foot syndrome. Background technique [0002] Hand-foot syndrome (HFS), also known as palmoplantar sensory loss erythema syndrome, is a relatively frequent dose-limiting local skin toxicity reaction, which can be cured by the new anthracycline pegylated liposomal doxorubicin, Capecitabine, fluorouracil, sorafenib and other chemotherapy drugs. HFS may appear at the earliest 3-5 days after the initial treatment, and its early symptoms include erythema, significant discomfort, swelling, or tingling on the palms and toes of the palms and toes, and blistering or even ulceration in severe cases; dark-skinned patients may be accompanied by pigmentation Calmness and thickening of the skin. HFS is most likely to appear in the palms and soles of the feet, and other parts such as the armpit, groin, waist, in...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61F7/02A61K9/70A61K36/56A61P17/00A61P25/02A61K31/4415
CPCA61F7/02A61K36/237A61K36/232A61K36/268A61K36/258A61K36/48A61K36/56A61K33/22A61K36/21A61K36/324A61K31/4415A61K9/7053A61K9/7046A61P17/00A61P25/02A61F2007/0036A61F2007/0045A61F2007/0226A61F2007/0261A61F2007/0287A61F2007/0219A61K2300/00
Inventor 王晴何欣贾辛婕王淼
Owner TIANJIN TUMOR HOSPITAL