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Method and system for predicting inferior perinatal outcome of gestational acute fatty liver mother and child

A perinatal, liver mother-infant technology, applied in the field of medicine, can solve problems such as the lack of high-risk factors, and achieve the effect of ensuring accuracy, improving accuracy, and improving prediction accuracy

Pending Publication Date: 2021-05-28
SHANDONG UNIV QILU HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In order to solve the problem of lack of existing high-risk factors, the present invention provides a method based on clinical information of patients and fetuses, such as basic characteristics, abnormal laboratory results and clinical manifestations, etc., for the screening and evaluation of high-risk factors for AFLP maternal and fetal adverse perinatal outcomes. Validated method and system, and use it to predict maternal and fetal adverse perinatal outcomes of acute fatty liver in pregnancy, in order to provide more personalized clinical guidance for the improvement of AFLP patients and their fetal adverse perinatal outcomes

Method used

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  • Method and system for predicting inferior perinatal outcome of gestational acute fatty liver mother and child
  • Method and system for predicting inferior perinatal outcome of gestational acute fatty liver mother and child
  • Method and system for predicting inferior perinatal outcome of gestational acute fatty liver mother and child

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Experimental program
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Embodiment

[0060] 1. Construct the AFLP patient information database according to the following entry and exit criteria,

[0061] Patient inclusion criteria:

[0062] (1) The patient's clinical information meets at least three of the following diagnostic indicators;

[0063] a) The patient's clinical information shows that the patient's clinical manifestations are abnormal; for example, one or more of nausea, vomiting, jaundice, vaginal bleeding, abdominal pain, dizziness, acid reflux, etc.;

[0064] b) Abnormal laboratory test indicators are shown in the patient's clinical information; for example, one or more of the abnormal indicators listed below: abnormal liver function, such as elevated transaminase, total bilirubin, and decreased albumin; renal function Impaired, such as increased creatinine, urea nitrogen, alkaline phosphatase, etc.; coagulation dysfunction, such as prolonged prothrombin time, partial thromboplastin time, and decreased fibrinogen level; abnormal blood routine, suc...

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Abstract

The invention provides a method and a system for predicting an end of a poor perinatal period of a pregnant acute fatty liver mother and child. The method comprises the following steps: screening bad perinatal period outcome high-risk factors of the gestational acute fatty liver mother and child, and constructing a high-risk factor and bad perinatal period outcome prediction model; the method for screening the bad perinatal outcome high risk factors of the pregnant acute fatty liver mother and child comprises the steps: constructing an AFLP patient information base, wherein the patient information base comprises clinical information of patients and fetuses; grouping the clinical information in the AFLP patient information base, obtaining risk factors, and confirming the end of a bad perinatal period; and screening out high-risk factors of poor perinatal outcome of maternal and child with acute fatty liver in gestation period. According to the method, the occurrence condition of the bad perinatal outcome of all gestational acute fatty liver patients and the fetuses thereof can be effectively predicted, and more personalized clinical guidance suggestions can be provided for improvement of the bad perinatal outcome of the AFLP patients and the fetuses thereof.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a method and a system for predicting adverse perinatal outcome of acute fatty liver during pregnancy. Background technique [0002] The information disclosed in this Background section is only intended to increase the understanding of the general background of the present invention, and is not necessarily taken as an acknowledgment or any form of suggestion that the information constitutes the prior art already known to those skilled in the art. [0003] Acute fatty liver of pregnancy (AFLP) is a rare obstetric emergency that poses a serious threat to the life safety of mother and fetus. The onset of AFLP is sudden, often in late pregnancy or early delivery. Because the prodromal symptoms of the disease are various and non-specific, timely and accurate diagnosis is very difficult. At the same time, the disease progresses rapidly, and within a short period of time, patients will develop a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/20G16H50/70G16H10/60G06N20/10G06N20/20
CPCG16H50/20G16H50/70G16H10/60G06N20/10G06N20/20
Inventor 宋坤潘惜雨孔北华李莉李晓褚然姚舒孟金玉
Owner SHANDONG UNIV QILU HOSPITAL
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