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Vitamin C and zinc sustained and controlled release tablet and preparation method thereof

A vitamin and controlled-release tablet technology, which is applied in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. Long-lasting and immune-boosting effect

Pending Publication Date: 2021-06-01
陕西思瑰瑞食品科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Humans cannot synthesize it by themselves and need to ingest it from the outside world. In addition to daily vitamin C intake, oral vitamin C tablets are a good way to supplement vitamin C. However, vitamin C is prone to chemical effects during long-term storage and transportation. Changes, the rapid release of a large amount of vitamin C in the human body will also cause unnecessary waste of drugs

Method used

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  • Vitamin C and zinc sustained and controlled release tablet and preparation method thereof
  • Vitamin C and zinc sustained and controlled release tablet and preparation method thereof
  • Vitamin C and zinc sustained and controlled release tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Vitamin C plus zinc sustained and controlled release tablet is composed of a tablet-shaped drug core and a sustained-release coating. The tablet-shaped drug core includes the following raw materials in parts by weight: 10 parts of vitamin C, 10 parts of zinc ion-containing substances, and the balance of water; The sustained-release coating includes the following raw materials in parts by weight: 20 parts of main film-forming agent, 10 parts of pregelatinized starch, 5 parts of toughening agent, 3 parts of anti-blocking agent, 2 parts of plasticizer, and 1 part of coloring agent , 1 part of additive, the balance of ethanol.

[0033] The preparation method of the vitamin C plus zinc sustained and controlled release tablet comprises the following steps:

[0034] (1) Take the vitamin C of parts by weight and pulverize it into powder, add zinc ion-containing substances of parts by weight, stir and mix evenly, add water, keep stirring to make it viscous, put it into a tablet ...

Embodiment 2

[0038] Vitamin C plus zinc sustained and controlled release tablet is composed of a tablet-shaped drug core and a sustained-release coating. The tablet-shaped drug core includes the following raw materials in parts by weight: 15 parts of vitamin C, 15 parts of zinc ion-containing substances, and the balance of water; The sustained-release coating includes the following raw materials in parts by weight: 80 parts of main film-forming agent, 20 parts of pregelatinized starch, 15 parts of toughening agent, 8 parts of anti-blocking agent, 6 parts of plasticizer, and 5 parts of coloring agent , 5 parts of additives, the balance of ethanol.

[0039] The preparation method of the vitamin C plus zinc sustained and controlled release tablet comprises the following steps:

[0040] (1) Take the vitamin C of parts by weight and pulverize it into powder, add zinc ion-containing substances of parts by weight, stir and mix evenly, add water, keep stirring to make it viscous, put it into a tab...

Embodiment 3

[0044] Vitamin C plus zinc sustained and controlled release tablet, which is composed of a tablet-shaped drug core and a sustained-release coating. The tablet-shaped drug core includes the following raw materials in parts by weight: 13 parts of vitamin C, 13 parts of zinc ion-containing substances, and the balance of water; The sustained-release coating includes the following raw materials in parts by weight: 60 parts of main film-forming agent, 15 parts of pregelatinized starch, 10 parts of toughening agent, 5 parts of anti-blocking agent, 4 parts of plasticizer, and 3 parts of coloring agent , 3 parts of additives, the balance of ethanol.

[0045] The preparation method of the vitamin C plus zinc sustained and controlled release tablet comprises the following steps:

[0046] (1) Take the vitamin C of parts by weight and pulverize it into powder, add zinc ion-containing substances of parts by weight, stir and mix evenly, add water, keep stirring to make it viscous, put it into ...

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Abstract

The invention relates to the technical field of vitamin C sustained release, in particular to a vitamin C zinc sustained and controlled release tablet and a preparation method thereof. The vitamin C zinc sustained and controlled release tablet comprises a tablet-shaped medicine core and a sustained-release coating; the tablet-shaped medicine core comprises the following raw materials in parts by weight: 10-15 parts of vitamin C, 10-15 parts of zinc ion-containing substances and the balance of water; and the sustained-release coating comprises the following raw materials: 20-80 parts of a main film-forming agent, 10-20 parts of pregelatinized starch, 5-15 parts of a toughening agent, 3-8 parts of an anti-blocking agent, 2-6 parts of a plasticizer, 1-5 parts of a coloring agent, 1-5 parts of an auxiliary agent and the balance of ethanol. Vitamin C and zinc are mixed, vitamin C and microelement zinc are supplemented at the same time, smooth proceeding of various enzyme reactions in a human body is facilitated, good toughness and wear resistance are achieved, long-acting constant-speed release is achieved through a sustained and controlled release coating, carrier protein on a cell membrane is actively transferred through zinc absorption, the release time is longer, short-term carrier saturation can be avoided, the release time and carrier transfer time are longer, and the absorption and utilization rate is improved.

Description

technical field [0001] The invention relates to the technical field of vitamin C sustained release, in particular to a vitamin C plus zinc sustained and controlled release tablet and a preparation method thereof. Background technique [0002] Vitamin C is one of the indispensable substances for human beings. It assists various enzyme reactions in the body. Vitamin C plays an important role in the formation of collagen. Collagen is an important substance for the development and repair of human tissue cells, gums, blood vessels, bones, and teeth; it helps the body absorb iron; it accelerates the consumption of vitamin C in a state of tension. Vitamin C participates in the oxidation-reduction process in the body, promotes the growth and development of the human body, enhances the body's resistance to diseases, promotes the formation of collagen in the intercellular substance, maintains the normal functions of teeth, bones, blood vessels and muscles, and enhances the detoxificat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/30A61K9/36A61K9/30A61K47/38A61K47/44A61K47/12A61P37/04A61P25/00A61P15/00A61P31/12A61K31/375
CPCA61K33/30A61K31/375A61K9/2866A61K9/282A61P37/04A61P25/00A61P15/00A61P31/12
Inventor 贾毅
Owner 陕西思瑰瑞食品科技有限公司
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