Liquid adhesive bandage and preparation method thereof

Abstract

The invention belongs to the field of a medical preparation, and particularly relates to a liquid adhesive bandage and a preparation method thereof. The liquid adhesive bandage disclosed by the invention comprises the following components in percentage by mass: 52.29% to 78% of antibacterial liquid, 8.51% to 29.5% of healing liquid and 10% to 20% of film-forming agent; based on the mass percentage of the liquid adhesive bandage, the healing liquid contains 0.01% to 0.5% of hyaluronic acid and 0.5% to 3% of asiaticoside; and the antibacterial liquid contains 0.09% to 0.9% of antibacterial peptide and 0.9% to 9% of chitosan. The liquid adhesive bandage disclosed by the invention has good air permeability and waterproofness, is fragrant in smell, is easy to strip after film formation, is short in film formation time, and has excellent antibacterial activity and an effect of promoting wound healing.

Description

technical field [0001] The invention belongs to the field of medical preparations, and in particular relates to a liquid wound dressing and a preparation method thereof. Background technique [0002] It is inevitable that accidents will occur in life and work to produce wounds. In the face of small wounds, abrasions, cuts and other superficial wounds and the care of the surrounding skin, wounds are usually treated with bandages to achieve compression, hemostasis, and protection. The purpose of wound surface, prevention of infection, and promotion of healing. However, the adhesive plaster used in ordinary wound plasters has poor air permeability, and the water vapor and sweat normally secreted by the human body cannot penetrate this layer of adhesive plaster, which will easily cause bacteria to grow and reproduce, and make the skin at the wound turn white, leading to subsequent infection; The adhesive layer makes it fixed on the skin outside the wound, which will more or les...

AI Technical Summary

Problems solved by technology

However, the adhesive plaster used in ordinary wound plasters has poor air permeability, and the water vapor and sweat normally secreted by the human body cannot penetrate this layer of adhesive plaster, which will easily cause bacteria to grow and reproduce, and make the skin at the wound turn white, leading to subsequent infection; The adhesive layer makes it fixed on the skin outside the wound, which will more or less prevent the wound from being completely isolated from the outside world. It is inevitable that water, bacteria or dust will enter the wound from the gap and cause wound infection; moreover, most ordinary wound adhesives All have a fixed size and size and are not suitable for all sizes of wounds

[0003] Based on the problems of air permeability, poor waterproofness, and inappropriate size of the above-mentioned wound pastes, the existing liquid wound pastes on the market can not be limited by size, and also have the advantages of waterproof and breathable, such as the liquid wound paste brand of Japan. Kobayashi Pharmaceutical Co., Ltd. and New Skin in the U.S., etc., because the existing liquid band-aids contain acrylate non-natural volatile medical glue, the liquid band-aids not only have the pungent smell of nail polish; in addition, the existing liquid band-aids There is also the problem that the waterproof film formed after it is applied to the affected area is not easy to fall off. When it is uncovered, it will cause pain, and even bleeding will cause secondary damage. Expensive and other issues, so further research is needed to develop a liquid bandage with a delicate smell, fast film formation, good waterproof and breathable properties, easy to remove, low cost, and simple preparation process

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