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Coating having virus killing function and formed on surface of article and coating method of coating

A virus-killing and article-killing technology, applied in botanical equipment and methods, devices for coating liquids on surfaces, coatings, etc., can solve the problem of preventing haloamine compounds from being retrieved, inability to complete the transcription process, and inability to produce specific proteins And other issues

Pending Publication Date: 2021-06-15
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, the researchers found that haloamine compounds also have a good killing effect on viruses. The nitrogen-halogen bond in the haloamine compound is hydrolyzed to release a strong oxidative halogen cation, which can denature the protein shell on the surface of the virus and cannot complete the genetic inheritance of the virus. The transcription process of the DNA or RNA of the substance cannot produce a specific protein that invades the living body, and there is no specific protein that binds to the host cell
However, no report on the use of halamine compounds to prevent COVID-19 has been retrieved

Method used

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  • Coating having virus killing function and formed on surface of article and coating method of coating
  • Coating having virus killing function and formed on surface of article and coating method of coating
  • Coating having virus killing function and formed on surface of article and coating method of coating

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Step 1, prepare polyallylamine solution, the solution concentration is 100mg / mL;

[0050] Step 2, preparation of available chlorine cation (Cl + ) content is a chlorinating agent solution of 5.00wt%;

[0051] Step 3, when the molar fraction m of the monomer repeating unit of the amino group of haloamination in the polyallylamine solution is m=0.4, calculate the consumption of required available chlorine cation (Cl+), then step 2 The prepared chlorinating agent solution is added dropwise in the prepared solution of step 1, and stirred while adding dropwise to make it react uniformly;

[0052] Step 4. Dialyzing the solution prepared in Step 3 to obtain a partially chloraminated polyamine derivative solution. Its concentration is 50mg / mL, and its available chloride cation (Cl + ) content is 2.00wt%;

[0053] Step 5, select cotton cloth as the substrate article (material) of coating;

[0054] Step 6. Treat the cotton cloth in an oxygen environment of a plasma cleaner f...

Embodiment 2

[0064] Step 1, prepare polyethyleneimine solution, the solution concentration is 100mg / mL;

[0065] Step 2, preparation of available chlorine cation (Cl + ) content is a chlorinating agent solution of 5.00wt%;

[0066] Step 3, when the molar fraction m=0.4 of the monomer repeating unit of the amine group of chlorination in polyethyleneimine solution, calculate required available chlorine cation (Cl + ), then the chlorinating agent solution prepared in step 2 is added dropwise in the prepared solution of step 1, and stirred while adding dropwise, to make its uniform reaction;

[0067] Step 4. Dialyzing the solution prepared in Step 3 to obtain a partially chloraminated polyamine derivative solution. Its concentration is 100mg / mL, and its available chloride cation (Cl + ) content is 2.00wt%;

[0068] Step 5, select cotton cloth as the substrate article (material) of coating;

[0069] Step 6. Treat the cotton cloth in an oxygen environment of a plasma cleaner for 5 minutes t...

Embodiment 3

[0077] Step 1, prepare poly-N-methylformamide solution, the solution concentration is 100mg / mL;

[0078] Step 2, preparation of available chlorine cation (Cl + ) content is a chlorinating agent solution of 3.00wt%;

[0079] Step 3, when the molar fraction m=0.4 of the monomer repeating unit of the amino group of chloramination in the N-methylformamide solution, calculate the required available chlorine cation (Cl + ), then the chlorinating agent solution prepared in step 2 is added dropwise in the prepared solution of step 1, and stirred while adding dropwise, to make its uniform reaction;

[0080] Step 4. Dialyzing the solution prepared in Step 3 to obtain a partially chloraminated polyamine derivative solution. Its concentration is 60mg / mL, and its available chloride cation (Cl + ) content is 2.50wt%;

[0081] Step 5, select cotton cloth as the substrate article (material) of coating;

[0082] Step 6. Treat the cotton cloth in an oxygen environment of a plasma cleaner f...

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Abstract

The invention relates to a coating having a virus killing function and formed on the surface of an article. The coating contains a partially haloaminated polyamine derivative; and a structural formula is [NRX]m[NHR]1-m, wherein R is H(CH2)n, n is 0-20, X is Cl, Br or I atom, m is the mole fraction of a haloaminated amino group monomer repeating unit and is equal to 0.1-0.9, and 1-m is the mole fraction of an amino group monomer repeating unit. Nitrogen-halogen bonds N-X exist in the partially haloaminated polyamine derivative, the nitrogen-halogen bonds produce a hydrolysis reaction when encountering water to release X<+> ions which have strong oxidizing property and can kill viruses, and the ions adhere to the surface of the article through amino groups in the partially haloaminated derivative and hydrogen bond acting force formed on the polar surface to form the coating with the virus killing function.

Description

technical field [0001] The invention relates to a coating with a virus-killing function formed on the surface of an article and a coating method thereof. [0002] technical background [0003] A virus is a submicroscopic pathogen that can only replicate and reproduce in the living cells of an organism. It is a non-cellular form composed of a nucleic acid molecule (DNA or RNA) and protein. An organic species between living and non-living organisms that lives on parasites. It is a piece of DNA or RNA wrapped in a protective shell. By virtue of the mechanism of infection, these simple organisms can use the host's cellular system to replicate themselves, but cannot grow and replicate independently. Viruses can infect all living organisms with cellular structures. Viruses spread in a variety of ways, and different types of viruses use different methods. For example: influenza virus can be spread by coughing and sneezing; norovirus can be spread by the hand-foot-mouth route, i.e...

Claims

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Application Information

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IPC IPC(8): D06M15/61D06M15/03C08B37/08C08G73/02C07C239/06A01N59/00A01P1/00B05D3/00B05D7/24C09D133/26C09D133/24C09D179/02C09D5/14C08F8/20C08F20/56D06M101/06
CPCD06M15/61D06M15/03C08G73/02C08B37/003C07C239/06A01N59/00B05D7/24B05D3/002C09D133/26C09D133/24C09D179/02C09D5/14C08F8/20D06M2101/06
Inventor 汪大洋王博解仁国
Owner JILIN UNIV
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