Stem cell composite preparation and preparation method thereof

Abstract

The invention discloses a stem cell composite preparation and a preparation method thereof, and belongs to the technical field of stem cell culture. The stem cell composite preparation comprises the following raw materials: a stem cell stock solution concentrated solution, non-crosslinked hyaluronic acid, water-soluble idebenone, nucleotide and vitamins. The yield of the stem cell paracrine related factors is improved through low-oxygen treatment, and non-crosslinked hyaluronic acid is introduced as a carrier, so that on one hand, the instant effect of the stem cell compound preparation in use is improved, and on the other hand, the diffusion speed of the stem cell paracrine factors to skin tissues is effectively controlled. Through adding the nucleic acid and idebenone, the synthesis of subcutaneous protein substances is increased, the antioxidant capacity of the skin is improved, the regulation of an endogenous skin cell microenvironment is changed into free radical resistance generated by exogenous ultraviolet rays, and the aim of rejuvenating the face is achieved on the whole.

Description

technical field [0001] The invention relates to the technical field of stem cell culture, and more specifically relates to a stem cell compound preparation and a preparation method thereof. Background technique [0002] Aging is a series of complex physiological processes that lead to a slowdown of metabolic and regenerative functions in the body. The effect of aging on facial aesthetics is of particular concern in modern society. The effects of aging on the face include: skin wrinkles, sagging, pigment changes, roughness, dryness, and loss of tensile strength, among others. The factors that cause skin phenotype changes related to skin age mainly include: 1) The collagen fibers produced by fibroblasts are reduced, which leads to the interference of the contact and communication process between skin cells in the cell matrix, resulting in thinning of skin thickness and elasticity. 2) Subcutaneous fat and muscle tissue atrophy with age, resulting in a decrease in facial tissu...

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Problems solved by technology

[0006] Related products in the prior art contain PRP (the full name of PRP is high-concentration platelet plasma, which is plasma containing high-concentration platelets made from one's own blood), which can only be applied to individual customization, and cannot be produced industrially, and the operation is relatively complicated. The preparation process risk of contamination

Or use dialysis when extracting effective substances from adult stem cells, resulting in limited active ingredients of the extract and low production efficiency

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