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High-safety mosquito-repelling gel and preparation method thereof

A high-safety, mosquito-repelling technology, applied in skin care preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as reducing the hydrolysis efficiency of mosquito-repelling active ingredients, and achieve prolongation of efficacy protection time, The effect of prolonging the protection time of mosquito repellent and slowing down the hydrolysis efficiency

Pending Publication Date: 2021-10-08
润本生物技术股份有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The invention provides a high-safety mosquito repellent gel and a preparation method thereof, adopts mosquito repellent active ingredients with a high safety factor, and at the same time reduces the hydrolysis efficiency of mosquito repellent active ingredients by establishing a special buffer system, so as to solve the problem of insecurity. The technical problem of improving the efficacy time limit of mosquito repellent gel while improving the safety of mosquito repellent gel

Method used

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  • High-safety mosquito-repelling gel and preparation method thereof
  • High-safety mosquito-repelling gel and preparation method thereof
  • High-safety mosquito-repelling gel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-3

[0046] A highly safe mosquito repellent gel prepared by the following steps:

[0047] S1. Mix carbomer, humectant and sterile water, keep stirring evenly, then raise the temperature to 85°C, keep warm, refer to Table 2 for the holding time, homogenize, and refer to Table 2 for the homogenization time to obtain the initial solution ;

[0048] S2, cooling the initial solution to 50°C, adding a neutralizing agent, and stirring evenly to obtain an intermediate solution;

[0049] S3. Add ethanol, mosquito repellent ester, triethyl citrate and preservative to the intermediate solution, stir evenly, and then obtain mosquito repellent gel;

[0050] Wherein, the neutralizing agent is triethanolamine.

[0051]Following table 2 is the processing parameter of the component, content and preparation process of raw material in embodiment 1-3:

[0052]

[0053]

[0054] Raw material component, content and process parameter in table 2-embodiment 1-3

Embodiment 4

[0056] A highly safe mosquito repellent gel, the difference from Example 3 is that triethanolamine is replaced by sodium hydroxide.

Embodiment 5

[0058] A highly safe mosquito repellent gel, the difference from Example 3 is that triethanolamine is replaced by aminomethyl propanol.

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Abstract

The invention discloses high-safety mosquito-repelling gel and a preparation method thereof, and relates to the technical field of mosquito-repelling products. The high-safety mosquito-repelling gel is prepared from the following raw material components: dimethyl phthalate, triethyl citrate, ethanol, carbomer, a humectant, a preservative, a neutralizer and sterile water. The preparation method comprises the following steps that S1, the carbomer, the humectant and the sterile water are mixed;2S, then a neutralizer is added for being uniformly stirred; and S3, the ethanol, the dimethyl phthalate, the triethyl citrate and the preservative are sequentially added, and uniformly stirred to obtain the mosquito-repelling gel. According to the high-safety mosquito-repelling gel and the preparation method thereof, triethyl citrate is adopted to construct a buffer system, hydrolysis of dimethyl phthalate can be greatly slowed down, the mosquito-repelling protection time is prolonged while the safety of the mosquito-repelling gel is guaranteed, and the requirements of consumers are met.

Description

technical field [0001] The invention relates to the field of mosquito repellent products, in particular to a highly safe mosquito repellent gel and a preparation method thereof. Background technique [0002] Summer is the peak season for mosquito infestation. Children's skin is relatively sensitive and tender. After being bitten by mosquitoes, it will leave red and swollen itchy bumps. If you don't pay attention to it later, scratching will lead to inflammation and damage. Moreover, mosquito bites can easily lead to mutual infection of infectious diseases Spread, cause trouble. Harmless physical mosquito repellent methods such as mosquito nets and window screens can only be used in fixed places. For uncontrollable places such as going out, mosquito repellent products can be effectively prevented. [0003] At present, the mosquito repellent products on the market are mainly spray-type mosquito repellent water, and a small part is smear-type mosquito repellent gel. The spray-...

Claims

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Application Information

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IPC IPC(8): A61K8/04A61K8/34A61K8/37A61K8/41A61K8/42A61K8/81A61Q17/02A61Q19/00
CPCA61K8/42A61K8/37A61K8/34A61K8/8147A61K8/042A61K8/41A61K8/375A61Q17/02A61Q19/007A61K2800/524
Inventor 孙金媛赵贵钦赵崇江王俊林陈意平佘奕河
Owner 润本生物技术股份有限公司
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