Traditional Chinese medicine composition for treating knee joint degenerative change and application thereof

Abstract

The invention relates to a traditional Chinese medicine composition for treating knee joint degenerative change and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-20 parts of radix angelicae pubescentis, 10-20 parts of radix clematidis, 3-9 parts of prepared kusnezoff monkshood root, 25-35 parts of garden balsam stem, 10-20 parts of kadsura pepper stem, 10-20 parts of cassia twig, 10-20 parts of caulis spatholobi, 10-20 parts of cynanchum paniculatum, 10-20 parts of lycopodium clavatum, 5-15 parts of safflower carthamus and 10-20 parts of cortex acanthopanacis. The radix angelicae pubescentis, radix clematidis, cynanchum paniculatum and cassia twig have the effects of warming and dredging channels and removing paralysis and are used as monarch drugs; the cortex acanthopanacis, prepared kusnezoff monkshood root, safflower carthamus and caulis spatholobi have the effects of dispelling cold and dampness and promoting blood circulation to arrest pain and are used as ministerial drugs; the lycopodium clavatum and garden balsam stem have the effects of relaxing muscles and tendons and relieving pain and are used as adjuvant drugs; the kadsura pepper stem has the effect of dredging channels and is used as a conductant drug; and all the drugs supplement each other and have a synergistic effect. Animal experiments show that the traditional Chinese medicine composition has a remarkable effect of treating the knee joint degenerative change and can be used for remarkably improving the knee joint pain degree, joint movement degree, swelling degree and gait of an animal model.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for treating knee joint pain caused by knee joint degenerative changes and its application. Background technique [0002] Knee degenerative disease, also known as osteoarthritis, osteoarthrosis, degenerative joint disease, hypertrophic arthritis, hypertrophic arthritis, senile arthritis, etc., is the most common chronic and progressive joint disease. Its pathological features are degeneration and destruction of articular cartilage, subchondral bone sclerosis, reactive hyperplasia of joint margins and subchondral bone, and osteophyte formation. Its clinical manifestations are knee joint swelling, pain, difficulty walking, standing up and squatting down. This disease belongs to the category of "arthritis" in traditional Chinese medicine. At present, it is generally believed that the root cause of this disease is th...

AI Technical Summary

Problems solved by technology

At present, there is no traditional Chinese medicine composition that has a significant curative effect on knee joint degenerative lesions such as the present application, and has few medicinal flavors and components.

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