The invention discloses a plaster for treating arthralgia and myalgia, which is prepared from notoginseng, orientvine, 40-50g of rhaphidophora decursiva, girald daphne bark, rubus multibracteatus, overall angelica, zedoary, stephania tetrandra, gentiana macrophylla, clematis root, chaenomeles speciosa, notopterygium root, radix angelicae pubescentis, erythrina bark, wooly datchmanspipe herb, american lopseed, drynaria, chuanxiong rhizome, mastic, roasted myrrh, notoginseng, pangolin, draconis sanguis, scorpion, menthol, rosin, bee wax and clove oil. The plaster has the functions of expelling pathogenic wind, eliminating dampness, dispelling cold, promoting blood circulation, activating meridians, relieving pain, eliminating swelling, dissipating blood stasis and strengthening muscles and bones. The plaster has a good effect on treating acute and chronic soft tissue injury, cervical spondylosis, scapulohumeral periarthritis, lumbar intervertebral disc protrusion and knee-joint pain.