Pharmaceutical composition for treating or preventing oral diseases
A composition and drug technology, applied in the directions of drug combination, oral care, pharmaceutical formula, etc., can solve the problems of difficulty in ensuring industrialization, complex preparation process, and numerous flavors of medicinal materials, and achieve good taste, high long-term safety, long-term conform to good effect
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Embodiment 1
[0060] Embodiments of the present invention will be described in detail below in conjunction with examples, but those skilled in the art will understand that the following examples are only for illustrating the present invention, and should not limit the scope of the present invention. The Scutellaria baicalensis extract used in the present invention can be extracted through the extraction process described in "Chinese Pharmacopoeia (2015 Edition)" or can be obtained commercially. Those who do not indicate the specific conditions in the examples, continue to twist according to the conventional conditions or the conditions suggested by the manufacturer. All reagents or instruments provided without manufacturer’s indication are commercially available conventional products. Below in conjunction with embodiment the feature of the present invention and performance are described in further detail: Embodiment 1: the preparation technology of light bamboo leaf extract, mulberry leaf e...
Embodiment 2
[0067] Embodiment 2, antibacterial effect and mouthfeel evaluation test
[0068] 1. Antibacterial activity of different ratios of active ingredients of the Chinese medicine composition of the present invention to periodontal pathogenic bacteria anaerobic bacteria
[0069] Anaerobic bacteria selection: Porphyromonas gingivalis (Porphyromonas.gingivalis, Pg) ATCC 33277,
[0070] Preparation of the test sample mother board: the active ingredients of the Chinese medicine composition of the present invention are provided by Sichuan Jishengtang Pharmaceutical Co., Ltd., and the weight percentages of each component are as follows;
[0071]
[0072]
[0073] Prepare test A, B, C with sterile water to make 100mg / ml mother solution, use DMSO to make test D into 400mg / ml mother solution, and make 100mg / ml according to the weight percentage of each component mentioned above. In a 96-deep well plate, use the corresponding solvent of the test product to perform 2-fold gradient diluti...
Embodiment 3
[0103] Preparation of toothpaste:
[0104] Prescription: 56g sorbitol, 10g glycerin, 16g hydrated silica, 2g sodium lauryl sulfate, 1.5g mint essence, 0.9g xanthan gum, 0.24g sodium fluoride, 0.2g sodium benzoate, 0.2g menthone glycerin ketal , Sucralose 0.14g, Scutellaria Baicalensis Extract 0.14g, Mulberry Leaf Extract 0.12g, Lotus Leaf Extract 0.12g, Bamboo Leaf Extract 0.12g, Borneol 0.01g, Menthol 0.01g, Purified Water 12.3g.
[0105] Production Method:
[0106] 1. Take the prescribed amount of sorbitol and vacuum inhale the main pot;
[0107] 2. Premixing: Dissolve the prescribed amount of sodium fluoride, sodium benzoate, baicalin extract, sucralose, light bamboo leaf extract, and lotus leaf extract with the prescribed amount of purified water first, stir the solution until dissolved, and premix for later use Add the prescribed amount of xanthan gum to the prescribed amount of glycerin, stir until it is evenly dispersed, and obtain the premixed second for later use; t...
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Abstract
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