Microneedle patch for drug delivery or biological fluid collection and preparation method thereof

A biological fluid and microneedle sticking technology, which is applied in the direction of medical devices, microneedles, and devices introduced into the body, can solve the problems of difficult biological fluid collection, many processing steps, and high processing costs, and achieve simple process and fluid communication The effect of extended time and low processing cost

Pending Publication Date: 2021-11-02
广州市智芯禾科技有限责任公司
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Conventional microneedle patch devices have the following disadvantages: 1. It cannot fit well with irregular skin, such as silicon-based microneedle arrays, because the substrate is hard; 2. The overall processing cost is high and the process Complicated, such as hollow microneedles, the overall processing procedures are more, and need to be carried out in a

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Microneedle patch for drug delivery or biological fluid collection and preparation method thereof
  • Microneedle patch for drug delivery or biological fluid collection and preparation method thereof
  • Microneedle patch for drug delivery or biological fluid collection and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0031] Example 1:

[0032] This example gives a specific embodiment of a microneedle patch collected by a drug delivery or biological fluid, such as Figure 1-3 As shown, including the patch base 1, uniformly opened on the patch substrate 1, and each side of the reservoir 3 is provided on both sides of the reservoir 3, and the microneedle 3 is opened to the side of the reservoir 2. The channel 7, the flow channel 7 is connected to the reservoir 2, and the microneedle 3 includes a base 4 coupled to the patch base 1, which is disposed above the body 5 above the top of the body 5, and the tip end 6.

[0033] Further, the patch substrate 1 uses a rectangular structure.

[0034] Further, the base 4 employs a circular table structure, and the main body 5 employs a cylindrical structure, the tip 6 adopts a conical structure.

[0035] Further, the convection channel 7 is located at the top of the tip 6, and the other end is in communication with the reservoir 2.

[0036] By adopting the ab...

Example Embodiment

[0039] Example 2:

Example Embodiment

[0040] This example gives a specific embodiment of a microneedle patch preparation method for drug delivery or biological fluid collecting, including the following steps:

[0041] Making template;

[0042] Making a microneedle patch.

[0043] Further, production template, including the following steps:

[0044] Three-dimensional graphic structure of the microneedles;

[0045] The design graphic structure is introduced into the laser-related system to perform three-dimensional laser lithography;

[0046] Drip the painting glue in the substrate;

[0047] After exposure to laser, the exposed area of ​​the negative-tone resistant resistance and the exposed area and the exposed area of ​​the positive-tone resistant resistant, to obtain a template of the microneedle patch.

[0048] Further, a microneedle patch, including the following steps:

[0049] Improve the first polymer material of the molten state into the template, form a micro-needle region, and the first polymer material is a ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a microneedle patch for drug delivery or biological fluid collection, which comprises a patch substrate, a plurality of liquid storage tanks are uniformly formed in the patch substrate, microneedles are arranged on the two sides of each liquid storage tank, flow guide channels are formed in the sides, close to the liquid storage tanks, of the microneedles, and the flow guide channels communicate with the liquid storage tanks; the microneedle comprises a base connected with the patch substrate, a main body arranged above the base and a tip end arranged at the top of the main body. The invention further discloses a preparation method of the microneedle patch, the microneedle patch is suitable for the technical field of transdermal drug delivery and transdermal biological sampling, firstly, the patch substrate is made of a flexible material and can be well attached to the skin; secondly, a way of opening a channel on the side surface of the microneedle is adopted, so that flow can be well guided, and channel blockage caused by interception of skin tissues is avoided; in addition, the whole manufacturing process does not need to be carried out in a super-clean environment, the overall machining cost is low, and the technology is simple and convenient.

Description

technical field [0001] The invention belongs to the technical field of transdermal administration and transdermal biological sampling, in particular to a microneedle patch for drug delivery or biological fluid collection and a preparation method thereof. Background technique [0002] Although hypodermic needles are commonly used for blood sampling and analysis, there are limitations to the application of this technology. Hypodermic needles are painful and scary for adults and children alike, require skilled medical operators to collect blood samples, and there are significant delays between blood extraction and test results. Additionally, blood analysis requires access to pathology infrastructure, which may not be available in remote areas or in emergency situations. Difficult venous access is encountered in different patient cohorts, namely infants, children, elderly, obese individuals with poor venous permeability, and emergencies such as shock. Drugs that are not bioava...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61M37/00
CPCA61M37/0015A61M2037/0023A61M2037/0046A61M2037/0053A61M2037/0061A61M2037/0038
Inventor 夏凯邓杨
Owner 广州市智芯禾科技有限责任公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap