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Self-lubricating antibacterial hydrophilic TPU as well as preparation method and application thereof

A hydrophilic and self-lubricating technology, which is applied in the field of preparation and self-lubricating antibacterial and hydrophilic TPU, can solve the problems of easy bacterial infection and poor antibacterial effect of the tube, so as to reduce the probability of infection and the intake of antibiotics input, solve the effect of slow release

Inactive Publication Date: 2021-11-23
厦门石破惊天材料科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 2. Because it is a long-term intervention, and part of the tube is exposed outside the body, it is easy to cause bacterial infection, which requires the tube itself to have antibacterial properties, but the current antibacterial effect of the tube is not good

Method used

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  • Self-lubricating antibacterial hydrophilic TPU as well as preparation method and application thereof
  • Self-lubricating antibacterial hydrophilic TPU as well as preparation method and application thereof
  • Self-lubricating antibacterial hydrophilic TPU as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] All of the following ingredients are commercially available:

[0035] Hydrophilic TPU resin (Tecophilic): Lubrizol Tecophilic HP-93A-100

[0036] Silver ion antibacterial agent: Swiss Sanitized silver ion antibacterial agent BCA21-61

[0037] Adhesive layer formulations are shown in the table below:

[0038] raw material Component (%) Tecophilic HP-93A-100 95 BCA21-61 5

[0039] Pour all the ingredients of the above formula into a mixer and mix for 10-15 minutes, and the TPU needs to be dried in a dehumidifier at 80°C for 4-6 hours in advance. The mixed raw materials are melted and extruded by a twin-screw extruder, and granulated.

[0040] Antibacterial TPU / medical TPU double-layer tube is extruded by two single-screw co-extrusion, refer to figure 1 , whose structure is as follows:

[0041] a) The outer layer 2 is TPU mixed with antibacterial silver ions, with a thickness of 0.08mm

[0042] b) The inner layer 1 is made of TPU material ...

Embodiment 2

[0044] All of the following ingredients are commercially available:

[0045] Hydrophilic TPU resin (Tecophilic): Lubrizol Tecophilic HP-93A-100

[0046] Silver ion antibacterial agent: Swiss Sanitized silver ion antibacterial agent BCA21-61

[0047] Adhesive layer formulations are shown in the table below:

[0048]

[0049]

[0050] Pour all the ingredients of the above formula into a mixer and mix for 10-15 minutes, and the TPU needs to be dried in a dehumidifier at 80°C for 4-6 hours in advance. The mixed raw materials are melted and extruded by a twin-screw extruder, and granulated.

[0051] Antibacterial TPU / medical PVC double-layer pipe is extruded by two single-screw co-extrusion, refer to figure 1 , whose structure is as follows:

[0052] a) The outer layer 2 is TPU mixed with antibacterial silver ions, with a thickness of 0.08mm

[0053] b) The inner layer 1 is made of PVC material with a hardness of about Shore 80A-90A (transparent or PVC-B20 with 20% bariu...

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Abstract

The invention provides self-lubricating antibacterial hydrophilic TPU as well as a preparation method and application thereof. The self-lubricating antibacterial hydrophilic TPU is prepared from the following components in parts by weight: 95 to 99 parts of hydrophilic thermoplastic polyurethane and 1 to 5 parts of an antibacterial agent. The hydrophilic thermoplastic polyurethane is Tecophilic TPU and has a water absorption rate of 50% to 150%. The antibacterial agent is a silver ion antibacterial agent. The self-lubricating antibacterial hydrophilic TPU is prepared by mixing the constitutional raw materials in proportion and then processing the formed mixture by using a double / single screw granulator. The self-lubricating antibacterial hydrophilic TPU is applied to a medical catheter which is of a double-layer structure comprising an inner layer and an outer layer, wherein the inner layer of the catheter is made of PVC or TPU, the outer layer of the catheter is made of the self-lubricating antibacterial hydrophilic TPU, and the medical catheter is one selected from a CVC, a PICC, a urethral catheter and a peritoneal dialysis catheter. The self-lubricating antibacterial hydrophilic TPU can effectively reduce the pain of catheterization / extubation of a patient, prolong the service life of a device and reduce the risk of bacterial infection.

Description

technical field [0001] The invention relates to the field of polymer material technology and medical application, more specifically, to a self-lubricating, antibacterial and hydrophilic TPU, a preparation method and its application. Background technique [0002] Interventional medical devices such as hemodialysis catheters (CVC), peripheral circulation catheters (PICC), peritoneal dialysis catheters, and urinary catheters have a large number of clinical applications. In addition to ensuring effectiveness and safety in clinical use, these medical devices also There are following problems: [0003] 1. The intervening tube body is required to have a low friction coefficient and lubricity, which is helpful for doctors / nurses to insert / extubate, and can reduce the pain of patients, but at present, it is generally solved by adding a disposable lubricant or coating. There is no lubricating effect due to the disappearance of the coating during extubation. For example, in the appli...

Claims

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Application Information

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IPC IPC(8): C08L75/04C08K3/08B32B27/40B32B27/06
CPCC08K3/08B32B27/40B32B27/08C08K2003/0806C08L2207/04C08L2203/18C08L75/04
Inventor 郝同辉
Owner 厦门石破惊天材料科技有限公司
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