Spina date seed capsule and preparation method thereof

A technology of jujube seeds and capsules, which is applied in the directions of capsule delivery, pharmaceutical formulations, and medical preparations with inactive ingredients, etc., can solve the problems of large film-forming water loss, prone to brittle cracking, poor toughness of the capsule shell, etc. The effect of improving performance, dense network structure, and improving mechanical properties

Active Publication Date: 2021-12-21
JIANGI WENIR NUTRITION HIGH TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, western medicine is mostly used for the treatment of insomnia. Western medicine mostly uses sedative and hypnotic drugs such as diazepam, which has better effect, but it is drug-dependent and has certain side effects. Suanzaoren Capsule is a capsule drug containing Suanzaoren, which can Effectively treats insomnia, but most of the capsules are made of natural polymer materials directly, which has high water loss, poor toughness of the capsule shell, and is prone to brittle cracks

Method used

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  • Spina date seed capsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The raw materials for the core include: Jujube Seed, Angelica, Polygala, Radix Paeoniae Alba, Poria, and Gardenia; and the raw materials for the capsule, which include 28 parts by weight of gelatin, 13 parts by weight of oyster shells, 20 parts by weight of vegetable oil, 0.4 parts of nano grade titanium dioxide and 10 parts by weight of a plasticizer, and the plasticizer is glycerin and triethyl citrate at a mass ratio of 1:1.

[0024] The core medicinal materials are made into decoction pieces (100 parts by weight of Suanzaoren, 90 parts by weight of Angelica sinensis, 90 parts by weight of Polygala, 80 parts by weight of Radix Paeoniae Alba, 70 parts by weight of Poria cocos, 50 parts by weight of Gardenia), add 1.5 times the amount of water, and heat Soak at 40°C for 1 hour, add water to decoct, combine the decoction liquid, filter, concentrate under reduced pressure to a relative density of 1.1 at 80°C, add ethanol to make the alcohol content reach 70%, refrigerate ...

Embodiment 2

[0031] The raw materials for the core include: Jujube Seed, Angelica, Polygala, Radix Paeoniae Alba, Poria, and Gardenia; and the raw materials for the capsule, which include 29 parts by weight of gelatin, 12 parts by weight of oyster shells, 20 parts by weight of vegetable oil, and 0.3 parts of titanium dioxide. and 19 parts by weight of a plasticizer, the plasticizer being glycerin and triethyl citrate at a mass ratio of 1:1.

[0032] The core medicinal materials are made into decoction pieces (100 parts by weight of Suanzaoren, 90 parts by weight of Angelica, 90 parts by weight of Polygala, 80 parts by weight of Radix Paeoniae Alba, 70 parts by weight of Poria cocos, 50 parts by weight of Gardenia), add 12 times the amount of water, and heat Soak at 50°C for 1 hour, add water to decoct, combine the decoction liquid, filter, concentrate under reduced pressure to a relative density of 1.15 at 80°C, add ethanol to make the alcohol content reach 70%, refrigerate and stand still,...

Embodiment 3

[0039] The raw materials for the core include: Jujube Seed, Angelica, Polygala, Radix Paeoniae Alba, Poria, and Gardenia; and the raw materials for the capsule, which include 28 parts by weight of gelatin, 13 parts by weight of oyster shells, 20 parts by weight of vegetable oil, and 0.5 parts of titanium dioxide. And 10 parts by weight of a plasticizer, the plasticizer is glycerin and triethyl citrate at a mass ratio of 1:1.

[0040] The core medicinal materials are made into decoction pieces (100 parts by weight of Suanzaoren, 90 parts by weight of Angelica sinensis, 90 parts by weight of Polygala, 80 parts by weight of Radix Paeoniae Alba, 70 parts by weight of Poria cocos, 50 parts by weight of Gardenia), adding 1.5-2 times the amount of water , heat at 40-50°C, soak for 1 hour, add water to decoct, combine the decoction liquid, filter, concentrate under reduced pressure to a relative density of 1.12 at 80°C, add ethanol to make the alcohol content reach 70%, refrigerate and...

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Abstract

The invention discloses a spina date seed capsule and a preparation method thereof, and relates to the field of a health-care food. The spina date seed capsule comprises a core raw material and a capsule raw material, wherein the capsule raw material comprises gelatin, oyster shells, vegetable oil, nanoscale titanium dioxide and a plasticizer. The gelatin and the oyster shell are used as raw materials, and the oyster shells contain rich calcium ions which can generate electrostatic attraction with carbonyl in the gelatin to play a role in coordination and complexation, so that the acting force of the gelatin and mineral particles is enhanced, the mechanical property of the capsule is improved, and the possibility of capsule fragmentation is reduced.

Description

technical field [0001] The invention relates to the field of health food, in particular to a jujube seed capsule and a preparation method thereof. Background technique [0002] At present, western medicine is mostly used for the treatment of insomnia. Western medicine mostly uses sedative and hypnotic drugs such as diazepam, which has better effect, but it is drug-dependent and has certain side effects. Suanzaoren Capsule is a capsule drug containing Suanzaoren, which can It can effectively treat insomnia, but the capsule material of most capsules is directly made of natural polymer materials to form a film, which has high water loss, poor toughness of the capsule shell, and is prone to brittle cracks. Contents of the invention [0003] The object of the present invention is to at least solve one of the technical problems in the prior art, and provide a Suanzaoren capsule and a preparation method thereof. [0004] Technical solution of the present invention is as follows:...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K47/46A61K47/02A61K47/44A61K47/42A61K36/744A61P25/20
CPCA61K36/725A61K36/232A61K36/69A61K36/71A61K36/65A61K36/076A61K36/744A61K9/4816A61K9/4825A61K47/44A61K47/02A61K47/46A61K9/1652A61P25/20A61K2300/00Y02A50/30
Inventor 阙素云甘小辉张美琴王珺陈波张蜻
Owner JIANGI WENIR NUTRITION HIGH TECH
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