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Hemodialysis concentrated solution and preparation method thereof

A technology of hemodialysis and concentrated solution, which is applied in blood diseases, pharmaceutical formulations, extracellular fluid diseases, etc. It can solve the problems of incomplete disinfection and sterilization, microbial growth and proliferation, and complicated processes, so as to increase the shelf life and facilitate storage and transportation. , the effect of inhibiting bacteria

Pending Publication Date: 2021-12-28
CHANGZHOU HUAYUE MINIMAL INVASIVE MEDICAL EQUIP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Hemodialysis concentrate is prone to microbial growth and proliferation. In the traditional configuration method, the process is complicated and the disinfection and sterilization are not thorough. Therefore, we have improved this and proposed a hemodialysis concentrate and its preparation method.

Method used

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  • Hemodialysis concentrated solution and preparation method thereof

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Embodiment

[0023] Example: such as figure 1 As shown, the hemodialysis concentrated solution of the present invention includes hemodialysis concentrated A liquid and hemodialysis concentrated B liquid, and the hemodialysis concentrated A liquid includes the following components: potassium chloride, magnesium chloride, sodium chloride, calcium chloride, pH value An aqueous solution of regulator and glacial acetic acid, hemodialysis concentrate B includes the following components: sodium bicarbonate, an aqueous solution of sodium bicarbonate and sodium chloride.

[0024] Among them, the content of each component of concentrated hemodialysis liquid A is potassium chloride 3-6g / L, magnesium chloride 7-15g / L, sodium chloride 70-120g / L, calcium chloride 4-8g / L, traditional Chinese medicine extract 2-6g / L, pH adjuster 3-9g / L and glacial acetic acid aqueous solution 10-26g / L.

[0025] Wherein, the content of each component of the hemodialysis concentrated liquid B is composed of 6-18 g / L sodium...

Embodiment 1

[0038] Embodiment one: step one: get hemodialysis concentrated A liquid and hemodialysis concentrated B liquid relevant solution, the content of each component of hemodialysis concentrated A liquid is potassium chloride 3-6g / L, magnesium chloride 7-15g / L, chlorine Sodium Chloride 70-120g / L, Calcium Chloride 4-8g / L, Traditional Chinese Medicine Extract 2-6g / L, pH Regulator 3-9g / L, Glacial Acetic Acid Solution 10-26g / L, Hemodialysis Concentration B The content of each component of the liquid is: sodium bicarbonate 6-18g / L, sodium bicarbonate 14-28g / L and sodium chloride aqueous solution 5-35g / L are put into the liquid mixing tank according to a certain ratio, and then poured into the It injects an appropriate amount of purified water, mixes and stirs, the stirring rate is 80-360rpm, and the stirring time is 25min-40min; Step 2: Filter the stirred liquid obtained in Step 1, and filter it with a filter aperture of 0.3μm; Step 3: Put the solution obtained in Step 2 into a filling b...

Embodiment 2

[0039] Embodiment two: step one: get hemodialysis concentrated A liquid and hemodialysis concentrated B liquid related solution, the content of each component of hemodialysis concentrated A liquid is potassium chloride 7-10g / L, magnesium chloride 11-19g / L, chlorine Sodium Chloride 74-124g / L, Calcium Chloride 8-12g / L, Traditional Chinese Medicine Extract 6-10g / L, pH Regulator 7-13g / L, Glacial Acetic Acid Solution 14-30g / L, Hemodialysis Concentration B The content of each component of the liquid is: sodium bicarbonate 10-22g / L, sodium bicarbonate 18-32g / L and sodium chloride aqueous solution 9-39g / L are put into the liquid mixing tank according to a certain ratio, and then poured into the It injects an appropriate amount of purified water, mixes and stirs, the stirring rate is 80-360rpm, and the stirring time is 25min-40min; Step 2: Filter the stirred liquid obtained in Step 1, and filter it through a filter aperture of 0.3μm ; Step 3: Put the solution obtained in Step 2 into a ...

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Abstract

The invention discloses a hemodialysis concentrated solution and a preparation method thereof. The preparation method comprises the following steps: step 1, taking related solutions of a hemodialysis concentrated solution A and a hemodialysis concentrated solution B, putting the related solutions into a solution preparation tank according to a certain proportion, injecting a proper amount of purified water into the solution preparation tank, and mixing and stirring; step 2, filtering the stirred liquid obtained in the step 1, wherein the stirred liquid is filtered through a filtering pore diameter of 0.3 mu m; step 3, disinfecting and sterilizing the solution obtained in the step 2, putting the sterilized solution into a filling barrel, and sealing and storing; and step 4, carrying out sampling detection on the sealed and stored product in the step 3. According to the hemodialysis concentrated solution and the preparation method thereof, growth and proliferation of bacteria and viruses in the hemodialysis concentrated solution can be effectively inhibited, and the preparation steps are simple and novel.

Description

technical field [0001] The invention relates to the technical field of hemodialysis concentrate, in particular to hemodialysis concentrate and a preparation method thereof. Background technique [0002] Hemodialysis is one of the renal replacement therapies for patients with acute and chronic renal failure. It drains the blood from the body to the outside of the body, passes through a dialyzer composed of countless hollow fibers, and contains an electrolyte solution (dialysate) with a similar concentration in the body inside and outside the hollow fibers, through diffusion, ultrafiltration, adsorption and The principle of convection conducts material exchange, removes metabolic waste in the body, maintains electrolyte and acid-base balance; at the same time removes excess water in the body, and returns the purified blood. In the process of hemodialysis, a reagent that plays a key role is hemodialysis fluid, which is the premise to ensure sufficient dialysis, and is an impor...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61P7/08A61K33/06A61K31/19A61K33/00
CPCA61K33/14A61K33/06A61K31/19A61K33/00A61P7/08A61K2300/00
Inventor 徐林立尚超曹金花
Owner CHANGZHOU HUAYUE MINIMAL INVASIVE MEDICAL EQUIP CO LTD
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