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Pharmaceutical composition for oral care and preparation method thereof

A technology for oral care and composition, which is applied in the field of pharmaceutical composition for oral care and its preparation, can solve problems such as not being suitable for daily medical care, achieve excellent oral cleaning effect, accelerate fading speed, and simple formula

Inactive Publication Date: 2022-01-04
山东康克尔医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, fresh clematis, dried clematis and clematis tea are mainly sold in the market; there are also a small number of clematis compound oral liquids and sprays used as hospital preparations for patients to treat diseases, but hospital preparations only For medical use in hospital patients, not suitable for daily healthcare
After searching, it has not been found that a certain simple formula of clematis preparation has excellent oral antibacterial effect

Method used

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  • Pharmaceutical composition for oral care and preparation method thereof
  • Pharmaceutical composition for oral care and preparation method thereof
  • Pharmaceutical composition for oral care and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Prescription: 300 mL of hypochlorous acid water with a concentration of 80 ppm, 1 mL of clematis extract, 60 mg of tea polyphenols, and 750 mL of purified water

[0025] Preparation method: Add 18 times the amount of purified water to the dried Auranthus clematis, soak for 15 minutes, heat in a water bath at 60°C for 30 minutes, extract twice in a row, combine the filtrates, concentrate the clematis clematis extract to 0.5 g / mL, and set aside.

[0026] Dissolve 60 mg of tea polyphenols in 100 mL of purified water and mix them evenly, mix them with 1 mL of Auranthus clematis extract and 300 mL of hypochlorous acid water with a concentration of 80 ppm, then add purified water to 750 mL, put it into a spray bottle, and get .

Embodiment 2

[0028] Prescription: 250 mL of hypochlorous acid water with a concentration of 80 ppm, 1.1 mL of clematis extract, 70 mg of tea polyphenols, and 750 mL of purified water

[0029] Preparation method: Add 18 times the amount of purified water to the dried clematis clematis, soak for 15 minutes, heat in a water bath at 65°C for 30 minutes, extract twice in a row, combine the filtrates, concentrate the clematis clematis extract to 0.5 g / mL, and set aside.

[0030] Dissolve 70 mg of tea polyphenols in 100 mL of purified water and mix it evenly, mix it with 1.1 mL of Auranthus clematis extract and 250 mL of hypochlorous acid water with a concentration of 80 ppm, then add purified water to 750 mL, put it into a spray bottle, and get .

Embodiment 3

[0032] Prescription: 350 mL of hypochlorous acid water with a concentration of 80 ppm, 1 mL of clematis extract, 80 mg of tea polyphenols, and 750 mL of purified water

[0033] Preparation method: add 17 times the amount of purified water to the dried Auranthus clematis, soak for 20 minutes, heat in a water bath at 65°C for 30 minutes, extract twice in a row, combine the filtrates, concentrate the clematis clematis extract to 0.6 g / mL, and set aside.

[0034] Dissolve 80 mg of tea polyphenols in 100 mL of purified water and mix them evenly, mix them with 1 mL of Auranthus clematis extract and 350 mL of hypochlorous acid water with a concentration of 80 ppm, then add purified water to 750 mL, put it into a spray bottle, and get .

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to a pharmaceutical composition for oral care and a preparation method thereof. The pharmaceutical composition mainly takes the anoectochilus formosanus extracting solution, hypochlorous acid and tea polyphenol as active ingredients, has an excellent oral cleaning effect, can improve oral pain and accelerate ulcer healing and fading speed, is remarkable in curative effect, safe, reliable and free of toxic and side effects, and has a wide clinical application prospect.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for oral care and a preparation method thereof. Background technique [0002] Oral ulcer, commonly known as "oral ulcer", is a common ulcerative injury disease that occurs in the oral mucosa. It is more common in the inner lip, tongue, tongue abdomen, buccal mucosa, vestibular groove, soft palate and other parts of the mucosa, in a round or oval shape. painful ulcers. When oral ulcers attack, the pain is severe and the local burning pain is obvious. In severe cases, eating and speaking will be affected. Systemic symptoms such as fever and lymphadenopathy. At present, the main treatment method for oral ulcers in China is topical application, which uses traditional Chinese medicine ingredients or glucocorticoids that have anti-inflammatory and analgesic effects and promote ulcer healing. [0003] Hand, foot and mouth disease is a common ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P1/02A61P31/14A61P31/02A61P29/00A61K31/353A61K33/20
CPCA61K36/898A61K33/20A61K36/82A61K31/353A61P1/02A61P31/14A61P31/02A61P29/00A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 董金呈
Owner 山东康克尔医疗器械有限公司
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