Supercharge Your Innovation With Domain-Expert AI Agents!

Combined preparation of traditional Chinese medicine effective components for chronic pharyngitis

A technology for chronic pharyngitis and active ingredients, applied to medical preparations containing active ingredients, active ingredients of anhydrides/acids/halides, drug combinations, etc., can solve problems such as the inability to maximize the use of active ingredients of drugs and the inability to predict the curative effect , to achieve the effect of no toxic side effects and good curative effect

Pending Publication Date: 2022-01-18
东阳市人民医院
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional medicine believes that the etiology and pathogenesis of this disease are mainly lung and kidney yin deficiency, relapse of wind-heat evil, dryness of the lungs and body fluid, and dystrophy of the throat, but lack of anti-inflammatory activity and possible mechanism of action on the active ingredients of related drugs It is impossible to predict the curative effect or maximize the use of active ingredients of drugs.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Combined preparation of traditional Chinese medicine effective components for chronic pharyngitis
  • Combined preparation of traditional Chinese medicine effective components for chronic pharyngitis
  • Combined preparation of traditional Chinese medicine effective components for chronic pharyngitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A traditional Chinese medicine oral liquid for chronic pharyngitis, comprising 15 parts of goldenrod, 15 parts of Asparagus, 10 parts of Scrophulariaceae, 15 parts of Radix Radix Rhizoma Radix, 15 parts of Rehmannia glutinosa, 7 parts of wild chrysanthemum, and 10 parts of forsythia in parts by weight 7 parts and licorice.

Embodiment 2

[0037] In view of Ophiopogon japonicus and wild chrysanthemum single use also have certain curative effect on the treatment of pharyngitis, in the compound prescription of Chinese medicine treatment of pharyngitis, Scrophulariae Radix Scrophulariae, Rehmannia glutinosa, Radix Glycyrrhizae etc. , 6 groups were set up in the experiment, which were model group 1, group 1 consisted of 15 parts of Ophiopogon japonicus + 7 parts of wild chrysanthemum, group 2 consisted of 10 parts of Scrophulariaceae, 15 parts of Rehmannia glutinosa, 7 parts of licorice, and 10 parts of forsythia 3 groups are the medicinal liquid of the wild chrysanthemum, 4 groups are the medicinal liquid of Solidago, and 5 groups are the medicinal liquid of embodiment 1 of the present invention.

[0038] Preparation of the drug: Weigh the corresponding drug according to the proportion of the formula, add appropriate amount of water to decoct twice, combine the drug solution, filter, concentrate to 100ml, centrifuge...

Embodiment 3

[0042] Preparation of the medicine: take the corresponding compound (as shown in Table 2) according to the proportion of the formula, add an appropriate amount of water to make a 20 μmol / L medicine solution, centrifuge the obtained medicine solution at 3000 rpm for 30 minutes, and take the supernatant to filter with a 0.22uM filter Sterilize and store in a 4°C refrigerator for later use.

[0043] Table 2

[0044] Experimental group formula Proportion 1 R126-G, R30 1:1 2 R30, R83 1:1 3 R83, R126-G 1:1 4 R126-G, R30, R83 2:1:1 5 R126-G, R30, R83 1:2:1

[0045] The effect of drug stimulation on inhibiting the inflammatory response of THP-1 cells: THP-1 cells in good growth state were treated with 1X10 per well ^6 Spread to 6-well plate, induce 24h under 50ng / uL PMA, change 1640 medium to recover and culture overnight. The control group was 1ug / mL LPS, and the experimental group was 500-fold diluted drug + LPS in 1640 medium f...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the technical field of traditional Chinese medicines, and discloses a combined preparation of traditional Chinese medicine effective components for chronic pharyngitis. The combined preparation of the traditional Chinese medicine effective components for chronic pharyngitis comprises at least two of compounds R126-G, R30 and R83, and can consist of solidago decurrens, asparagus cochinchinensis, radix scrophulariae, radix ophiopogonis, dried rehmannia roots, wild chrysanthemum flowers, fructus forsythiae and liquorice roots. The preparation has the effects of clearing heat, detoxifying and relieving sore-throat, can be used for treating diseases such as pharyngalgia, dry throat, cough and less phlegm caused by chronic pharyngitis, and has a very good clinical application effect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a combined preparation of active ingredients of traditional Chinese medicines for chronic pharyngitis. Background technique [0002] Pharyngitis is an inflammatory immune disease. Due to the influence of various factors such as air pollution and climate, the incidence of laryngitis is as high as 30%-50%. It has become a common and frequently-occurring disease in clinical practice. There is still an upward trend. Clinically, it is mainly divided into acute and chronic pharyngitis. Acute pharyngitis is mainly caused by bacterial infection or secondary bacterial infection after viral infection. Chronic inflammation of submucosal tissue and lymphoid tissue, which can be diffuse or limited to the nasopharynx, oropharynx, or hypopharynx, mainly manifested by pharyngeal pain, foreign body sensation, itching, burning sensation, irritation, and hoarseness Wait. ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/7048A61K31/19A61K31/201A61K31/202A61K31/235A61K31/352A61K31/366A61K36/8968A61P11/04
CPCA61K31/366A61K31/7048A61K31/352A61K31/19A61K31/202A61K31/201A61K31/235A61K36/28A61K36/8965A61K36/808A61K36/8968A61K36/804A61K36/287A61K36/634A61K36/484A61P11/04A61K2300/00
Inventor 张慧慧金银芝
Owner 东阳市人民医院
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com