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Traditional Chinese medicine Li medicine composition for reducing ovarian reserve function, preparation method and application thereof

A technology of ovarian reserve and composition, which is applied in the field of traditional Chinese medicine Li medicine composition and its preparation, can solve the problems of lack of local characteristics and innovation, and the curative effect needs to be further improved, so as to achieve broad market prospects and development value, and improve the local microenvironment , Low toxicity and side effects

Active Publication Date: 2022-02-25
HAINAN MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are some traditional Chinese medicine compositions on the market for the treatment of decreased ovarian reserve function, but most of the ingredients are traditional Chinese medicine ingredients such as invigorating the kidney, invigorating the spleen and soothing the liver in the mainland. Traditional classic prescriptions are rarely used, and they lack local characteristics and innovation , and its efficacy needs to be further improved

Method used

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  • Traditional Chinese medicine Li medicine composition for reducing ovarian reserve function, preparation method and application thereof
  • Traditional Chinese medicine Li medicine composition for reducing ovarian reserve function, preparation method and application thereof

Examples

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Effect test

Embodiment 1

[0023] The compatibility of every 1 payment in the present embodiment is:

[0024] Rehmannia glutinosa 20g, Guojianglong 15g, Angelica 15g, Paeoniae Alba 15g, Polygonatum 20g, Cornus officinalis 12g, Pueraria 20g, Caulis Spatholobus 20g, Cuscuta 20g, Jianqu 10g, Agarwood 5g, and licorice 3g.

[0025]Preparation method: (1) take each raw medicinal material according to parts by weight and put it in a multifunctional extraction tank, add 8 to 12 times the amount of total medicinal materials and soak in water for 0.5 to 1.5 hours; (2) decoct for 1 to 2 hours, filter, and take The filtrate is set aside; (3) add 5 to 8 times the amount of water of the total medicinal materials again, decoct for 1 to 1.5 hours, filter, and take the filtrate for use; (4) combine the two filtrates, concentrate under reduced pressure, and vacuum dry to obtain the compound Chinese medicine extraction thing. In addition, the obtained traditional Chinese medicine compound extract and pharmaceutically acc...

Embodiment 2

[0027] The difference between this embodiment and embodiment 1 is compatibility, and the preparation method is the same as embodiment 1, and the compatibility of every 1 payment of the present embodiment is:

[0028] Rehmannia glutinosa 19g, Guojianglong 16g, angelica 14g, white peony root 16g, sealwort 19g, dogwood 13g, kudzu root 19g, milletus spatholobus 21g, dodder 19g, jianqu 11g, agarwood 4.5g, and licorice 3.5g.

Embodiment 3

[0030] The difference between this embodiment and embodiment 1 is compatibility, and the preparation method is the same as embodiment 1, and the compatibility of every 1 payment of the present embodiment is:

[0031] Rehmannia glutinosa 21g, Guojianglong 14g, Angelica 16g, Paeoniae Alba 14g, Polygonatum 21g, Cornus officinalis 11g, Pueraria 21g, Caulis Spatholobus 19g, Cuscuta 21g, Jianqu 9g, Agarwood 5.5g, and licorice 2.5g.

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Abstract

The invention provides a traditional Chinese medicine Li medicine composition for reducing an ovarian reserve function. The traditional Chinese medicine Li medicine composition is prepared from 18-22 parts of radix rehmanniae preparata, 13-17 parts of entada phaseoloides, 13-17 parts of radix angelicae sinensis, 13-17 parts of radix paeoniae alba, 18-22 parts of rhizoma polygonati, 10-14 parts of fructus corni, 18-22 parts of radix puerariae, 18-22 parts of caulis spatholobi, 18-22 parts of semen cuscutae, 8-12 parts of Jianqu, 4-6 parts of agilawood and 2-4 parts of radix glycyrrhizae. The invention further provides a corresponding traditional Chinese medicine Li medicine preparation and application thereof. According to the invention, the traditional Chinese medicine Li medicine composition can effectively increase the blood supply of ovary, improve the local microenvironment of the ovary and the uterus, and further increase the number of sinus follicles by adjusting the hypothalamus-pituitary-ovary reproductive axis, increasing the reaction of the ovary to gonadotropin and adjusting internal secretion, so that the clinical treatment effect is improved, the clinical symptoms of patients are improved, and the outcome of DOR and infertility is improved; and the traditional Chinese medicine Li medicine composition has low toxic and side effects, low price, local characteristics and wide market prospect and development value.

Description

technical field [0001] The invention relates to a Li medicine preparation, in particular to a Li medicine composition of a traditional Chinese medicine for reducing ovarian reserve function, a preparation method and application thereof. Background technique [0002] With the change of people's lifestyle and concept of fertility, women's childbearing age continues to move backward, the global fertility rate is declining year by year, and the incidence of infertility is increasing year by year. The results of epidemiological surveys show that the incidence of infertility among the population of childbearing age in my country is as high as 15%-20%, and the cumulative number of patients exceeds 60 million. Especially after the opening of the two-child and three-child policy in my country, elderly women become infertile Among the main infertility patients, decreased ovarian reserve (Diminished ovarian reserve, DOR) is an important pathogenic factor causing infertility in women of ...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P15/00
CPCA61K36/804A61K36/11A61K36/232A61K36/71A61K36/65A61K36/8969A61K36/40A61K36/488A61K36/486A61K36/39A61K36/43A61K36/00A61K36/835A61K36/484A61P15/00A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 刘英莲陈应奇岳雯谢毅强周夏芝李凯
Owner HAINAN MEDICAL COLLEGE
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