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Information storage method based on oligonucleotide chip hybridization

An oligonucleotide and information storage technology, applied in the field of information storage based on oligonucleotide chip hybridization, can solve the problems of poor information reading and writing accuracy, low storage density, slow reading and writing speed, etc., and achieves good parallelism , The effect of high information storage density and cost improvement

Pending Publication Date: 2022-02-25
WUHAN INST OF VIROLOGY CHINESE ACADEMY OF SCI +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] In order to solve the defects existing in the current technology, aiming at the problems of low storage density, poor information reading and writing accuracy, slow reading and writing speed and high storage cost in the existing DNA hybridization storage technology, the purpose of the present invention is to provide an oligonucleotide-based chip hybrid information storage method

Method used

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  • Information storage method based on oligonucleotide chip hybridization
  • Information storage method based on oligonucleotide chip hybridization

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Embodiment

[0039] The target information writing method in this application is to map the binary code converted from the original information into the sequence arrangement of several oligonucleotide coding strands on the chip, and then make an oligonucleotide chip with information The physical object; the information reading method is to hybridize the complementary fluorescent probe with the coding strand on the chip, detect the hybridized fluorescent signal through the chip scanner, obtain the coding strand combination of each site on the chip, and then use the decoding software to restore the original information. This application realizes the access of multiple complex file formats through oligonucleotide chip hybridization, with good parallelism and high signal-to-noise ratio, and has obvious advantages in access speed and accuracy compared with storage technologies based on long-chain DNA synthesis and sequencing. Advantage.

[0040] The oligonucleotide chip used in the present inve...

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Abstract

The invention discloses an information storage method based on oligonucleotide chip hybridization, which comprises the following target information writing steps: (1) converting target information into a binary code, then segmenting the binary code into a plurality of fields, each field corresponding to a site on an oligonucleotide chip, and each site comprising N binary digits; (2) mapping the 1 / 0 value on the N binary digits of each site into a presence / absence combination of N oligonucleotide coding chains to obtain a combination list of oligonucleotide coding chains needing to be added to all the sites on the oligonucleotide chip; and (3) fixing the oligonucleotide coding chains in the sites on the surface of the oligonucleotide chip in a covalent bond manner according to the oligonucleotide coding chain combination list, thereby completing the writing of the target information on the oligonucleotide chip. According to the invention, the access of various complex file formats is realized, the parallelism is good, the signal-to-noise ratio is high, the access speed is high, and the accuracy is good.

Description

technical field [0001] The invention belongs to the technical field of information storage, in particular to an information storage method based on oligonucleotide chip hybridization. Background technique [0002] With the rapid development of Internet, cloud computing, 5G communication, artificial intelligence and other fields, all kinds of digital information generated by human society are increasing exponentially, and the supply of storage media with silicon-based microelectronics as the mainstream is becoming more and more difficult to meet the demand. Storage issues are becoming increasingly prominent. In addition, silicon-based microelectronic storage systems not only have limited storage capacity, but also have a short storage time, are easily damaged, and have poor anti-interference performance. Therefore, the existing data information storage technology is facing serious bottlenecks, and it is urgent to find new storage media. [0003] Deoxyribonucleic acid (DNA) ...

Claims

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Application Information

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IPC IPC(8): G11C11/54G06N3/12
CPCG11C11/54G06N3/123
Inventor 刘翟张翼飞贾李佳王海华刘海舟张东裔张心怡
Owner WUHAN INST OF VIROLOGY CHINESE ACADEMY OF SCI
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