Beam shaping body with rotating target body

A technology of rotating target and shaping body, used in X-ray/γ-ray/particle irradiation therapy, radiotherapy, treatment, etc., can solve the problem that the neutron flux cannot meet the effect of treating deep tumors, unfavorable processing and manufacturing, and accelerator end hazards and other problems, to achieve the effect of improving epithermal neutron flux, convenient assembly and disassembly, and improving epithermal neutron flux

Pending Publication Date: 2022-03-25
CHINA SPALLATION NEUTRON SOURCE SCI CENT +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] (1) The retarder is a cone-shaped moderator formed in one piece. The moderator with this structure is not conducive to processing and manufacturing, and the neutron flux after moderation cannot meet the effect of treating deep tumors;
[0007] (2) The proton incident pipe is hollow cylindrical, and the hollow cylindrical channel tends to make more neutrons leak from this area, the utilization rate is not high, and it will also cause harm to the accelerator end

Method used

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  • Beam shaping body with rotating target body
  • Beam shaping body with rotating target body
  • Beam shaping body with rotating target body

Examples

Experimental program
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Effect test

Embodiment 1

[0049] Such as figure 1 As shown, the present invention proposes a beam shaper with a rotating target body, which includes a proton beam channel and a rotating target. Taking the incident direction of protons as the positive direction, one end of the proton beam channel is provided with an accelerator, and the other end A rotating target is set, with the proton incident point as the front end, and the outlet as the rear end (that is, the epithermal neutron beam ejection end), it can be known that the rotating target is set at the end of the proton beam flow channel.

[0050] The beam shaping body also includes a moderator, a reflector surrounding the moderator and the proton beam channel, a thermal neutron absorbing layer adjacent to the moderator, and a gamma shielding layer adjacent to the thermal neutron absorbing layer , and a collimator arranged at the neutron outlet in the beam shaping body; in addition, the outer diameter of the thermal neutron absorbing layer is greate...

Embodiment 2

[0053] Such as figure 2 As shown, this embodiment is optimized on the basis of the foregoing embodiment 1. Specifically, the moderator in this embodiment is in the shape of a cylindrical stepped shaft, and the number of the stepped shaft segments is 2 to 10, preferably 2 to 8 paragraphs, preferably 4 paragraphs. Those skilled in the art can also understand in this way: with the proton incident place as the front end, the moderator can include a front end body, several middle end bodies and a rear end body in turn, and the front end body, middle end body and rear end body form a cylindrical ladder Shaft-shaped moderater body, the number of stepped shaft segments of the mid-end body is 0-8, preferably 0-6, and most preferably 2; Different diameters show a gradually decreasing distribution (those skilled in the art can easily understand that: with the direction of proton incident as the positive direction, the front end body, middle end body and rear end body are gradually decr...

Embodiment 3

[0058] Such as image 3 As shown, this embodiment is further optimized on the basis of the foregoing embodiment 2. Specifically, there is a gap between the rear end body (the stepped shaft section with the smallest outer diameter) and the reflector in the process of this embodiment, and the designed The gap should not be too large, too large a gap will significantly increase the fast neutron component of the outlet, the gap should not be too small, too small a gap will limit the increase in the superthermal neutron component of the outlet, so the gap range is 1 to 20mm , preferably 10mm, which can increase the leakage of epithermal neutrons at the outlet, improve the flux of epithermal neutrons, and (the stepped shaft section with the smallest outer diameter) the rear end body is adjacent to the thermal neutron absorbing layer, which has a relatively good economy.

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Abstract

The invention discloses a beam shaping body with a rotating target body, which comprises a proton beam duct, a rotating target, a moderator, a reflector surrounding the moderator and the proton beam duct, a thermal neutron absorption layer adjacent to the moderator, a gamma shielding layer adjacent to the thermal neutron absorption layer, and a collimator arranged in the beam shaping body, the device is characterized in that a target body container used for installing a rotating target is further arranged in the beam shaping body, and the target body container is communicated with the proton beam flow hole channel and arranged in the reflector and the moderator; the rotating target comprises a rotating shaft and a target body fixed at the end of the rotating shaft, and the target body is detachably mounted in the target body container and arranged at the tail end of the proton beam duct. The target body container is arranged in the moderation body and the reflector, and the depth of the target body penetrating into the moderation body is not less than 50mm, so that recoil neutrons can be sufficiently moderated, and the epithermal neutron flux of an outlet is also improved.

Description

technical field [0001] The invention relates to the technical field of BNCT boron neutron capture therapy, in particular to a beam shaping body for deep tumor treatment. Background technique [0002] At present, photon or charged particle therapy is limited by the nature of the radiation. While killing tumor cells, it will also cause great damage to normal tissues in the area where the radiation passes. Moreover, for multilineage glioblastoma and melanoma Such highly radiation-resistant tumor cells are often ineffective by traditional radiation therapy. The neutron capture therapy, which has less radiation damage to normal tissues around the tumor and has a high relative biological effect in the target area, relies on the specific accumulation of boron-containing drugs in tumor cells, and cooperates with precisely regulated neutron beams to provide more radiation than traditional radiation. Better cancer treatment options. [0003] Boron Neutron Capture Therapy (BNCT) uses...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N5/10
CPCA61N5/1077A61N2005/109
Inventor 胡志良梁天骄傅世年张锐强
Owner CHINA SPALLATION NEUTRON SOURCE SCI CENT
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