Hydrogel carrying traumatology yellow water and preparation method thereof
A hydrogel and solvent technology, applied in medical science, bandages, etc., can solve problems affecting wound repair, short drug effect, heavy workload, etc., achieve long-lasting antibacterial and anti-inflammatory activity, effective microbial barrier, and prevent fluid formation Effect
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Embodiment 1～3
[0030] Examples 1-3: Verification of degree of alcoholysis and frozen gelation
[0031] Three kinds of PVA with the same molecular weight and different degrees of alcoholysis were respectively selected, and a PVA solution with a mass fraction of 15% was prepared with water, and gelation experiments were carried out in a refrigerator at -20°C with different freezing times and different cycle times. The gel conditions are shown in Table 1, and Table 1 shows the gelation results of the hydrogels prepared in Examples 1-3 of the present invention.
[0032] The preparation process is as follows:
[0033] Mix PVA with water, heat to dissolve, then let it stand for defoaming;
[0034] Add the PVA aqueous solution quantitatively into the plastic mold, place it horizontally in the freezer, freeze for a certain period of time, take it out and let it dissolve at room temperature for a period of time. Freeze once and thaw once as a cycle. After a certain number of cycles, the PVA soluti...
Embodiment 4～6
[0040] Embodiments 4-6: Molecular weight and frozen gelation verification:
[0041] Three kinds of PVA with the same degree of alcoholysis and different molecular weights were respectively selected to prepare a PVA solution with a mass fraction of 15%, and gelation experiments were carried out in a refrigerator at -20°C with different freezing times and different cycle times. As shown in Table 2, Table 2 shows the gelation results of the hydrogels prepared in Examples 4-6 of the present invention.
[0042] The preparation process is as follows:
[0043] Mix PVA with water, heat to dissolve, then let it stand for defoaming;
[0044] Add the PVA aqueous solution quantitatively into the plastic mold, place it horizontally in the freezer, freeze for a certain period of time, take it out and let it dissolve at room temperature for a period of time. Freeze once and thaw once as a cycle. After a certain number of cycles, the PVA solution is prepared into a PVA hydrogel.
Embodiment 4
[0047] The experimental results of Examples 4-6 show that the PVAs of the three selected molecular weights can form gels except that the 1-time 2h group in Example 4 cannot form gels. In actual use, the molecular weight can be selected according to the needs (viscosity, strength, etc.). The follow-up test of this application selects the 1799 type to carry out the hydrogel preparation and optimization experiment containing "Shangke Yellow Water".
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