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Oral care composition containing methyl salicylate

A technology of methyl salicylate, oral care, applied in the field of oral care

Pending Publication Date: 2022-03-29
HAWLEY & HAZEL BVI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, despite the extensive and long history of use of methyl salicylate in oral care products, the stability and effective release of methyl salicylate in the composition has also made its use a challenge

Method used

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  • Oral care composition containing methyl salicylate
  • Oral care composition containing methyl salicylate
  • Oral care composition containing methyl salicylate

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment

[0075] Method for evaluating the mouthfeel of wintergreen flavor

[0076] 1) Establishment of the evaluation team

[0077] Select 30 qualified sensory evaluators with reference to GB / T16291.1-2012 and GB / T12311-2012;

[0078] 2) Scoring criteria, the reviewer's correction of the evaluation criteria of holly flavor

[0079] Accurately weigh 1g, 2g, 5g, 10g of methyl salicylate, and weigh 10g of poloxamer, add it to 500ml of pure water and stir, so that the methyl salicylate is completely dissolved in the water evenly, and dilute to 1L with pure water , the holly flavor intensity is 1 point, 2 points, 7 points, 13 points respectively, and the holly flavor intensity of purified water is 0 point;

[0080] Take 20 mL of the above-mentioned reference sample solution, spit it out after fully gargling for 30 seconds (do not gargle with clear water), and evaluate the intensity of the wintergreen taste in the oral cavity at this time. The evaluator evaluates on a 15cm scale according ...

Embodiment 1-2

[0083] Embodiment 1-2, comparative example 1-5

[0084] Embodiment 1-2 and Comparative Example 1-5 are configured according to the formula in Table 1, and subjects are recruited to score the wintergreen flavor of the composition after being placed at room temperature for one week:

[0085] Table 1

[0086]

[0087] As can be seen from Table 1, all examples and comparative examples adjust the formulation pH with the buffer salt of pH7, and the pH values ​​of the formulations of examples and comparative examples are close, and the mass percent of methyl salicylate in the composition is 0.9%. In the formula of Example 1, silicon dioxide was used as an abrasive, and sorbitol was used as a humectant. At this time, the wintergreen score score of the composition was 9.4; in the formula of Example 2, calcium hydrogen phosphate was used as an abrasive, and sorbitol was used as a moisturizing agent. At this time, the wintergreen flavor score was 9.5; in comparative example 1, silic...

Embodiment 3-6, comparative example 6-7

[0090] Embodiment 3-6, comparative example 6-7 are configured according to the formula of Table 2, and recruit subjects to score the wintergreen flavor of the composition after being placed at room temperature for a week:

[0091] Table 2

[0092]

[0093] For convenience of comparison, the formula of Example 1 is listed in Table 2.

[0094] As can be seen from Table 2, when the pH value of the composition was 5.5, the holly flavor score of the composition was 7.7, but when the pH dropped to 5.2, the holly flavor score decreased significantly, only 4.8; When the pH was increased to 6.0, the wintergreen score increased to 9.5, and when the pH was increased to 6.4, the wintergreen score remained at 9.5. When the pH was further increased to 7.0, the wintergreen score remained at 9.4. When the pH was increased to At 7.8, the holly flavor score was 8.2, with a downward trend, but the downward trend was small, but when the pH was further increased to 8.2, the holly flavor score de...

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PUM

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Abstract

The invention provides an oral care composition containing methyl salicylate. The oral care composition comprises 1) methyl salicylate, 2) a humectant, 3) an abrasive and 4) other orally acceptable carriers, the moisturizing agent is sorbitol; the abrasive is one or a combination of calcium hydrophosphate or silicon dioxide, and the pH value of the composition ranges from 5.5 to 7.8. According to the oral care composition, methyl salicylate can be fully released, so that consumers can better perceive the holly flavor of the composition.

Description

technical field [0001] The invention relates to the technical field of oral care, in particular to an oral care composition containing methyl salicylate. Background technique [0002] Methyl salicylate, also known as methyl o-hydroxybenzoate, oil of wintergreen, also known as birch oil, sweet birch oil, methyl salicylate, tea seed oil. Molecular formula is C 8 h 8 O3, with a molecular weight of 152.15, is a colorless or light yellow, or light yellow-red transparent oily liquid with a strong aroma of wintergreen oil. Natural products exist in essential oils such as wintergreen oil, wintergreen oil, birch oil, green tea seed oil, clove oil, jasmine oil, tuberose oil, xiaodang medicinal oil, tea oil, ylang ylang oil, as well as cherry, apple, Strawberries in juice. Insoluble in water, soluble in general organic solvents such as ethanol, ether, and glacial acetic acid. It is easy to change color when exposed to air. The main purpose is to be used in the formula of daily ch...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/24A61K8/25A61K8/34A61K8/37A61Q11/00
CPCA61K8/37A61K8/345A61K8/25A61K8/24A61Q11/00
Inventor 陈晓斌周康邹晓斌高琳梁志雄
Owner HAWLEY & HAZEL BVI
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