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Sleep-promoting composition and sleep-promoting essential oil

A sleeping essence and formula technology, which can be used in pharmaceutical formulations, drug combinations, nervous system diseases, etc., can solve problems such as insignificant improvement effects, and achieve the effects of improving cardiovascular function, improving sleep quality, and promoting sleepiness.

Active Publication Date: 2022-04-01
GUANGDONG UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Publication No. CN106729068A Chinese patent provides a kind of external energy oil that can help sleep. It takes a long time to achieve the effect of sleep improvement, and the improvement effect is not obvious

Method used

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  • Sleep-promoting composition and sleep-promoting essential oil

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1 Prescription for sleeping and sleeping aids and its preparation

[0035] 1. Preparation of various prescriptions for sleep aid

[0036] Lavender oil, evening primrose oil, jasmine oil, bergamot oil, seabuckthorn oil and ylang-ylang oil are extracted by steam distillation. The specific extraction steps are as follows:

[0037] (1) Weigh 200 g of pulverized sample powder and place it in a 5000 mL round bottom flask.

[0038] (2) Add 3500mL deionized water and soak for 12 hours respectively.

[0039] (3) Steam distillation for 4 hours to obtain lavender oil, evening primrose oil, jasmine oil, bergamot oil, seabuckthorn oil and ylang-ylang oil.

[0040] (4) Stir and mix the obtained essential oils evenly in different proportions, the rotating speed of the stirring conditions is 900r / min, and the stirring time is 3min, to obtain final product.

[0041] 2. According to the dosage in Table 1, prepare the prescription for sleeping and sleeping aids

[0042] Table ...

Embodiment 2

[0044] Embodiment 2 sleeping essential oil and preparation thereof

[0045] 1. Prepare sleeping essential oil according to the dosage in Table 2

[0046] Table 2. Proportion of sleeping essential oils

[0047]

[0048] 2. The preparation method of sleeping essential oil

[0049] (1) Weigh 200 g of pulverized sample powder and place it in a 5000 mL round bottom flask.

[0050] (2) Add 3500mL deionized water and soak for 12 hours respectively.

[0051] (3) Steam distillation for 4 hours to obtain lavender oil, evening primrose oil, jasmine oil, bergamot oil, seabuckthorn oil and ylang-ylang oil.

[0052] (4) Obtain lavender oil, evening primrose oil, jasmine oil, bergamot oil, seabuckthorn oil, ylang-ylang flower oil and dehydrated alcohol to mix in different proportions, the rotating speed of the stirring condition is 1000r / min, and the stirring time is 5min , that is.

Embodiment 3

[0053] Efficacy test of embodiment 3 sleeping essential oil

[0054] The positive effects of the present invention on improving sleep will be further described below through animal experiment data.

[0055] 1. Experimental animals ICR-grade male BALB / C mice, weighing between 20 and 22 g, were provided by Guangdong Medical Experimental Animal Center. Mice were housed in individually ventilated positive and negative pressure animal cages, maintained at controlled temperature (20±2°C) and humidity (60±15%), and maintained a 12-hour light / dark cycle. Food and water were freely available during the rearing period, and they were acclimatized 7 days before the formal experiment.

[0056] 2. Drug management: sleeping essential oils 1-11 prepared according to the prescriptions in Table 2.

[0057] 3. Drug administration to animals: The mice were randomly divided into 12 groups according to body weight, namely: control group and experimental drug group. The experimental drug group was ...

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Abstract

The invention relates to a sleep-aiding formula and sleep-aiding essential oil, the sleep-aiding formula comprises lavender oil, evening primrose oil, jasmine flower oil, bergamot oil, sea buckthron oil and cananga odorata flower oil, the sleep-aiding formula is a combined formula of essential oil extracted from natural edible plant medicines, and the sleep-aiding formula can relieve mood, tranquilize and allay excitement and shorten sleep time. The invention further develops the peaceful essential oil which can effectively improve the sleep quality, has the effects of replenishing blood and soothing the nerves, condensing qi and clearing away the heart-fire, and calming and hypnotizing, and pointedly solves the problem of insomnia caused by emotion anxiety, restlessness, difficulty in falling asleep and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to a sleeping aid prescription and sleeping essential oil. Background technique [0002] Statistics show that about one-third of the people in the world have sleep dysfunction, and sleep problems will have a great negative impact on people's physiology and psychology. And along with socioeconomic development and increasingly fierce competition, the number of patients with sleep disorders is on the rise every year. In order to solve the above problems, various medicines, health care products and daily products with functions of improving sleep quality and treating sleep disorders have been developed and applied one after another. [0003] At present, the methods for the treatment of insomnia include drug therapy, muscle relaxation, hypnosis, suggestion therapy, behavior therapy, etc. At present, the main method in medicine is to use drug...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P25/20A61P9/00
Inventor 张蓝月石耀辉罗怡杰吴显仪赵庚梁晓欣向洪平李春莲宋一帆
Owner GUANGDONG UNIV OF TECH
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