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Preparation method and application of compound double-flower preparation

A compound double-flowering and compound technology, which is applied in the direction of antiviral agents, pharmaceutical formulas, and medical preparations with non-active ingredients, can solve problems such as affecting clinical efficacy, destroying effective ingredients, and unstable product quality, and achieves a universal Adaptability, easy large-scale production, and the effect of improving antibacterial and heat-clearing curative effect

Pending Publication Date: 2022-04-12
YUANSHENG SUYUANG BIOLOGICAL SCI TECH BEIJING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, the inventor found that the co-decoction of honeysuckle and Andrographis paniculata in the prescription will cause the reaction of chlorogenic organic acids and andrographolide compounds in honeysuckle, destroying the active ingredients, resulting in unstable product quality and affecting clinical efficacy.

Method used

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  • Preparation method and application of compound double-flower preparation
  • Preparation method and application of compound double-flower preparation
  • Preparation method and application of compound double-flower preparation

Examples

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preparation example Construction

[0025] A method of preparing a compound twist preparation, including:

[0026] Extract volatile oil with honeysuckle for raw materials, and combined to obtain volatile oil binders;

[0027] Extract the residue after extracting the oil and silver, and concentrate on the frying method.

[0028] Put the wearing a decoction method for extracting, concentrating, and getting a heart-loses;

[0029] The forsythia, the blue root is mixed, and the decoction method is extracted, concentrated, resulting in the foil, and the blue root of the plate;

[0030] The wearing a heart liqueur is mixed with a furbage, forsythia, and a blue root of the plate.

[0031] The mixed thick paste is mixed with honeysuckle ointment, and then the volatile oil comprise, mix well, resulting in a compound twist Chinese medicine composition;

[0032] The compound twist Chinese medicine composition is made into a Chinese medicine preparation.

[0033] In some embodiments, the dosage form of the Chinese medicine prep...

Embodiment 1

[0044] First, prescription

[0045] Honeysuckle 25kg, forsythia 25kg, wearing a heart 25kg, Board root 25kg

[0046] Second, the preparation process

[0047] 1, honeysuckle

[0048] 1) HKC volatile oil extraction: Take 25kg of gold and silver flowers, extract volatile oil for 2 h with flow water vapor method, collect volatile oil; volatilize oil, dissolve β-cyclodextrin, dissolve, add volatile oil ethanol solution, continue the constant temperature, cool to room temperature, After 24 hours of the refrigerator was placed in a 4 ° C, filtration was carried out, and the coated material was allowed to dry at 60 ° C for 4 h in the incubator, i.e., volatile oil combinations, spare;

[0049] 2) After the gold and silver flower medicinal materials, the residue after volatilizing oil, plus 8 times water, for the first time, boiling water, extract 2 times, 1 h, filtrate each time, mixed with filtrate, concentrated into a thick paste, spare.

[0050] 2, wearing heart

[0051] Take the porn l...

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Abstract

The invention belongs to the field of traditional Chinese medicine, and relates to a preparation method and application of a compound double-flower preparation, and the preparation method comprises the following steps: extracting volatile oil from honeysuckle as a raw material, and carrying out clathration to obtain a volatile oil clathrate compound; extracting residues obtained after extracting the volatile oil from the honeysuckle by adopting a decoction method, and concentrating to obtain honeysuckle thick paste; extracting common andrographis herb, fructus forsythiae and indigowoad root by adopting a decoction method, and concentrating to obtain thick paste; uniformly mixing the herba andrographitis thick paste, the fructus forsythiae and the radix isatidis thick paste, and performing alcohol precipitation to obtain mixed thick paste; uniformly mixing the mixed thick paste with the honeysuckle thick paste, adding the volatile oil inclusion compound, and uniformly mixing to obtain the compound double-flower traditional Chinese medicine composition; and preparing the compound double-flower traditional Chinese medicine composition into a traditional Chinese medicine preparation. Honeysuckle and andrographis paniculata are independently extracted, subjected to alcohol precipitation and then included with beta-cyclodextrin, the stability of chlorogenic acids and andrographolides can be guaranteed, the bitter taste of the chlorogenic acids and andrographolides can be effectively covered, and the taste is improved.

Description

Technical field [0001] The present invention belongs to the field of Chinese medicine, and in particular, the method of preparation and application of compound double-flowers formulations. Background technique [0002] The information disclosed in the background is disclosed only to increase the understanding of the overall background of the present invention, and is not necessarily considered to admit or imply that the information is intended to be a prior art known to those skilled in the art. [0003] Compound twicroaf formulation is made of gold and silver flowers, forsythia, wearing hearts, and blue roots, with heat and detoxification, hypophytic swelling, for wind and heat. The symptoms are mainly seen in fever, headache, nasal congestion, runny nose, sore throat, swallow, swallowing, tonsil redness. Including compound duplex granules, compound double flower oral liquid, compound double floral film and other oral formulations. [0004] The compound double flower prescriptio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/634A61K9/08A61K9/16A61K47/36A61K47/26A61K47/69A61P11/00A61P11/04A61P31/04A61P31/12
Inventor 门毅
Owner YUANSHENG SUYUANG BIOLOGICAL SCI TECH BEIJING
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