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Thaflavin composition, preparation method and application

A theaflavin and composition technology, applied in the field of theaflavin composition and preparation, can solve the problems of oral flora imbalance, obvious side effects, excessive intake of fluorine, etc., achieve antibacterial taste, improve extraction effect, increase yield rate effect

Pending Publication Date: 2022-04-26
JIANGSU DEHE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the anti-caries products mainly fall into the following categories: one is fluorine-containing preparations (such as fluoride-containing toothpaste), which are not cleaned or swallowed by mistake, which can easily lead to excessive intake of fluoride, which has potential health hazards; the other is mouthwash containing antibacterial drugs. Due to the obvious side effects such as broad-spectrum sterilization and drug resistance, long-term continuous use can easily cause oral flora imbalance and become the cause of various oral diseases

Method used

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  • Thaflavin composition, preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027]The theaflavin composition comprises the following components: 5 parts of theaflavins, 80 parts of black plum extract, 60 parts of honeysuckle extract, 90 parts of cassia seed extract and 4 parts of licorice extract. The preparation method of the ebony extract includes the steps of extraction, filtration, re-extraction, re-filtration, concentration, and drying; the extraction step is as follows: remove the core and pulverize the ebony, dry it at 15°C for 1 hour to constant weight, and add water It is 8 times of the dry weight of black plum, and boiled for 25 minutes; the re-extraction step is: adding water to the filter cake obtained in the filtering step and boiling for 15 minutes, and the amount of water added is 5 times of the dry weight of black plum; the concentration step is: filtering and re-extracting The filtrates obtained in the filtration step were combined and concentrated, and the concentration was stopped when the solid content reached 92%, and the obtained ...

Embodiment 2

[0029] The theaflavin composition comprises the following components: 25 parts of theaflavins, 120 parts of black plum extract, 80 parts of honeysuckle extract, 110 parts of cassia seed extract and 15 parts of licorice extract. The preparation method of the ebony extract includes the steps of extraction, filtration, re-extraction, re-filtration, concentration, and drying; the extraction step is as follows: the ebony is denuclearized and pulverized, dried at 25°C for 3 hours to constant weight, and the amount of water added It is 15 times of the dry weight of black plum, and boiled for 65 minutes; the re-extraction step is: adding water to the filter cake obtained in the filtering step and boiling for 60 minutes, and the amount of water added is 12 times of the dry weight of black plum; the concentration step is: filtering and re- The filtrates obtained in the filtration step were combined and concentrated, and when the solid content reached 98%, the concentration was stopped, a...

Embodiment 3

[0031] The theaflavin composition comprises the following components: 10 parts of theaflavins, 100 parts of black plum extract, 70 parts of honeysuckle extract, 100 parts of cassia seed extract and 10 parts of licorice extract. The preparation method of the ebony extract includes the steps of extraction, filtration, re-extraction, re-filtration, concentration, and drying; the operation of the extraction step is: remove the core and pulverize the ebony, dry it at 20°C for 2 hours to constant weight, and add water It is 10 times of the dry weight of black plum, and boiled for 30 minutes; the re-extraction step is: adding water to the filter cake obtained in the filtering step and boiling for 30 minutes, and the amount of water added is 10 times of the dry weight of black plum; the concentration step is: filtering and re- The filtrates obtained in the filtration step were combined and concentrated, and the concentration was stopped when the solid content was 95%, and the obtained ...

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Abstract

The invention discloses a theaflavin composition as well as a preparation method and application thereof, and the theaflavin composition is prepared from the following components in parts by weight: 5 to 25 parts of theaflavin, 80 to 120 parts of fructus mume extract, 60 to 80 parts of honeysuckle flower extract, 90 to 110 parts of semen cassiae extract and 4 to 15 parts of liquorice root extract. The oral care solution is simple to prepare, homologous in medicine and food, suitable for human use, high in safety, excellent in bacteriostatic effect and capable of being used for oral care. The invention has the advantages of low raw material cost, obvious cost advantage, industrialization, stable and controllable quality and stronger application prospect.

Description

technical field [0001] The invention belongs to the technical field of medical care, and in particular relates to a theaflavin composition, preparation method and application. Background technique [0002] Theaflavin is a natural pigment of large aromatic rings formed by fermentation and oxidation of catechins in tea. It was first discovered in black tea and is the main active substance in black tea. It has strong physiological activity. Known as the brain gold in tea. Due to the powerful effects of theaflavins, the research on theaflavins has become a hot topic in the medical circles all over the world. Since the 1980s, scientific and technological workers in my country have been continuously researching on theaflavins, and have carried out corresponding clinical research. Experiments have finally uncovered the pharmacological effects of theaflavins, and with the deepening of research, more and more functions of theaflavins have been discovered. Its main functions and appl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/49A61K36/736A61P1/02A61P31/04A61Q11/00A61K31/353
CPCA61K8/9789A61K8/498A61Q11/00A61K31/353A61K36/736A61K36/355A61K36/482A61K36/484A61P1/02A61P31/04A61K2800/5922A61K2800/84A61K2236/331A61K2236/51A61K2300/00
Inventor 任雪音刘剑宏浦平南曹后建
Owner JIANGSU DEHE BIOTECH
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