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A detection method, detection device and computer-readable storage medium for prothrombin time

A technology for prothrombin time and detection method is applied in the field of prothrombin time detection method, detection device and computer-readable storage medium, and can solve the problems affecting the detection accuracy of prothrombin time and the like

Active Publication Date: 2022-08-09
可孚医疗科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the existing technology, it is difficult to avoid the interference of pulse noise and salt and pepper noise during smoothing, thus affecting the detection accuracy of prothrombin time; error

Method used

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  • A detection method, detection device and computer-readable storage medium for prothrombin time
  • A detection method, detection device and computer-readable storage medium for prothrombin time
  • A detection method, detection device and computer-readable storage medium for prothrombin time

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Experimental program
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Effect test

Embodiment 1

[0043] see figure 1 , this embodiment discloses a schematic flowchart of a preferred prothrombin time detection method, including:

[0044] Raw data collection: drop the sample to be tested into the inlet of the prothrombin time electrochemical test paper, and collect the raw data at preset time intervals to obtain parameter data M ; the parameter data Mis the data on the impedance-time curve or the current-time curve;

[0045] Median filtering: on parametric data M Perform median filtering and smoothing to obtain a smooth curve; the mathematical expression of median filtering is:

[0046] ;

[0047] of which: Z i is the value of the filtered output, z i for the first i point value, N * Represents a set of positive integers; the specific steps of processing are as follows:

[0048] Step ①, to parameter data M in the i points are processed to obtain the first i point before and after v points, a total of 2 v +1 point; of which: i is greater than or equal to 2 ...

Embodiment 2

[0086] see figure 2 , this embodiment discloses a preferred prothrombin time detection device, including a central control module 21 , a data acquisition module 22 , a data processing module 23 and a user interface module 24 .

[0087] The central control module 21 uses the MCU chip, and is responsible for the overall control of the data acquisition module, the data processing module and the user interface module.

[0088] The data acquisition module 22 includes an electrochemical test paper and a sample inlet. After the sample to be tested is dropped into the sample inlet, the electrical signal generated during the enzymatic reaction can be detected by the electrochemical test paper, and the raw data such as the electrical signal can be collected. Obtain the parameter data, and then transmit the parameter data to the data processing module through the central control module.

[0089] The data processing module 23 is mainly used to realize the processing, storage and transmiss...

Embodiment 1）

[0091] The data storage module is used to store parameter data, detection results, patient information, operator information, etc., which is not specifically limited in this embodiment.

[0092] The data transmission module is used to receive the parameter data transmitted by the data acquisition module 22, and to transmit detection results, patient information, operator information, etc. to the user interface module 24, which is not specifically limited in this embodiment.

[0093] The user interface module 24 includes buttons and a display screen, the buttons are used to set instrument parameters and playback test results; the display screen is used to display detection information, patient information and operator information, etc., which is not specifically limited in this embodiment. .

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Abstract

The present invention provides a method for detecting prothrombin time. The method includes collecting raw data of a sample to be tested to obtain parameter data; smoothing the parameter data by a median filtering method to obtain a smooth curve; Multi-Gaussian fitting is performed on the curve of the Gaussian function to obtain the eigenvalues ​​of the characteristic parameters of the Gaussian function; the eigenvalues ​​of the characteristic parameters of the Gaussian function are screened through multi-condition judgment; according to the screened eigenvalues, a formula is constructed and the prothrombin time is calculated. . The present invention also provides a prothrombin time detection device and a computer-readable storage medium, wherein the detection device includes a data acquisition module and a data processing module. The advantages of the present invention lie in that when detecting prothrombin time, the signal-to-noise ratio of the detection result can be improved, and the interference of noise on the detection accuracy of prothrombin time can be avoided; the influence of asymmetry on the Gaussian fitting result can be reduced, and the index correction can be alleviated. Computational difficulty of asymmetric Gaussian fitting functions.

Description

technical field [0001] The invention relates to the technical field of electrochemical detection, in particular to a detection method, detection device and computer-readable storage medium for prothrombin time. Background technique [0002] Prothrombin time is an important screening test to check factors of exogenous coagulation system and related inhibitors, and it is also the main means of oral anticoagulant therapy. The conventional detection methods of prothrombin time include optical method, magnetic circuit method, electrochemical method and so on. However, the optical method is susceptible to specific plasma interference, and the magnetic circuit method is easily affected by the quality of the magnetic beads and the smoothness of the cup wall; the electrochemical method is convenient, fast, simple, and easy to use. Condensation monitoring and other aspects play an important role. [0003] Based on the electrochemical method, the basic principle of the prothrombin ti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06K9/00G01N33/86C12Q1/56
CPCG01N33/86C12Q1/56G06F2218/04G06F2218/08
Inventor 夏海艳全昌云王新天
Owner 可孚医疗科技股份有限公司
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