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Preclinical animal aerosol inhalation administration device

A technology of atomized inhalation and drug delivery device, which is applied in therapeutic nebulizers, medical science, veterinary instruments, etc. It can solve problems such as pollution, respiratory tract injury drug dosage requirements, and large body exposure, etc., to improve survival rate , reduce the atomization administration time, and promote the effect of air flow

Pending Publication Date: 2022-07-08
HARBIN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention aims to solve the existing technical problems of preclinical animal delivery through the respiratory tract and nebulization inhalation, which easily cause damage to the respiratory tract, large drug dosage requirements, and systemic exposure pollution, and provides a preclinical animal nebulization inhalation method. drug delivery device

Method used

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  • Preclinical animal aerosol inhalation administration device
  • Preclinical animal aerosol inhalation administration device
  • Preclinical animal aerosol inhalation administration device

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0039] Embodiment 1: This embodiment is a preclinical animal atomization inhalation drug delivery device, such as Figure 1-Figure 6 As shown, the oxygen supply source 1, the first connecting pipe 2, the monitoring box 3, the oxygen sensor 4, the carbon dioxide sensor 5, the second connecting pipe 6, the atomizer 7, the bracket 8, the suction pipe 9, the atomizing liquid Drop recovery bottle 10, atomization tube 11, recovery tube 12, upper cover 13, partition 14, air circulation barrel 15, fan 16, storage basket 17, foam soft plug 18, inhalation mask 19 and side cover 20;

[0040] The air outlet of the oxygen supply source 1 is communicated with the air inlet 3-1 of the monitoring box 3 through the first connecting pipe 2, and the air outlet 3-2 of the monitoring box 3 is connected to the atomizing pipe 11 through the second connecting pipe 6. The air inlet at the upper end is connected; in the inner cavity of the monitoring box 3, the partition plate 14 is fixed horizontally ...

specific Embodiment approach 2

[0056] Embodiment 2: The difference between this embodiment and Embodiment 1 is that the atomizer 7 is a jet atomizer, a vibrating mesh atomizer or an ultrasonic atomizer. Others are the same as the first embodiment.

specific Embodiment approach 3

[0057] Embodiment 3: The difference between this embodiment and Embodiment 1 or 2 is that the inhalation mask 19 is an anesthesia mask, made of transparent material, which can monitor the atomization state of the animal at any time, and the anesthesia mask is a mature commodity, which is convenient for Purchase, can be replaced regularly. Others are the same as in the first or second embodiment.

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Abstract

The invention discloses a preclinical animal aerosol inhalation administration device, and relates to an aerosol inhalation administration device. The invention aims to solve the technical problems that the existing preclinical animal respiratory tract delivery and aerosol inhalation administration mode is easy to cause injury to the respiratory tract, large in drug dosage demand and exposed and polluted in the whole body. Compared with an existing whole-body atomization device, the preclinical animal aerosol inhalation administration device has the advantages that only the mouth and the nose are exposed in an atomization space, the number of exposed parts is small, animal fur is effectively prevented from being contaminated with drugs, skin irritation caused by fur adhesion is prevented, administration dosage errors caused by animal licking after fur adhesion are prevented, and the clinical animal aerosol inhalation administration device is simple in structure and convenient to use. Meanwhile, medicine waste is avoided. The aerosol inhalation device comprises the multiple inhalation pipes, multiple animals can be subjected to aerosol inhalation synchronously at the same time, the multiple inhalation pipes are equally spaced by 360 degrees, the requirement that n is larger than or equal to 3 of experimental animals is met, and the condition that the same group of experimental animals inhale equal amount of medicine synchronously at the same time is guaranteed.

Description

technical field [0001] The present invention relates to a preclinical animal drug delivery device. Background technique [0002] Respiratory system diseases are common and frequently-occurring diseases that seriously endanger human health, bring a heavy burden to the society and the national economy, and are accompanied by the problem of irrational drug use in clinical practice. Aerosol inhalation therapy is one of the important treatment methods for respiratory system-related diseases, and is widely used at home and abroad because of its clinical application advantages. Aerosol inhalation is a direct drug delivery method targeting the respiratory tract and lungs. It has the advantages of fast onset of action, high local drug concentration, low dosage, convenient application and less systemic adverse reactions. of treatment. Aerosol inhalation has been used for the treatment and prevention of bronchial asthma, cystic fibrosis, chronic obstructive pulmonary disease (COPD) a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61D7/04A61D7/00A61M11/00
CPCA61D7/04A61D7/00A61M11/00A61M11/005A61M11/001Y02A50/20
Inventor 吴丽娜王凯琦
Owner HARBIN MEDICAL UNIVERSITY
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