Shuangjinlian oral liquid for curing cold and influenza, and its preparing method

A technology of Jinlian oral liquid and influenza, which is applied in the field of medicine, can solve the problems of one-time oral dosage, fever reduction, slow pain relief, and inconvenience for patients, and achieve the effect of inhibiting multiple influenza viruses, high content of active ingredients, and small prescription volume

Inactive Publication Date: 2004-05-26
HENAN TALOPH PHARMACEUTICAL STOCK CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, compared with western medicines, there are also disadvantages of slow fever reduction and slow pain relief.
In addition, the above-mentioned oral liquid also has the problem that the amount of medicine in the prescription is relatively large, and the one-time oral dosage is too much, which brings inconvenience to the patient.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The present embodiment adopts following proportioning and process step to realize:

[0020] a, superfinely pulverize 30% of Shuanghua (honeysuckle), 15% of nasturtium, 30% of forsythia, 15% of Bupleurum bupleuri and filter through a fine sieve of > 300 mesh, and put it into a 60°C After soaking in water for 2 hours, the medicinal solution is dynamically extracted by pump circulation, and the extracted medicinal solution is then dynamically soaked in water at a temperature of 60°C for 1.5 hours, then combined and decocted, filtered, and concentrated to relative After the density is 1.20 (measured at 80°C), slowly add ethanol when the medicinal solution is cooled to 40°C, and fully stir when the alcohol content reaches 70%. After standing for 12 hours, take the supernatant, Recover ethanol under reduced pressure until there is no alcohol smell, and set aside;

[0021] b. Slice 10% Scutellaria baicalensis, add water and decoct three times, the first time for 2 hours, the ...

Embodiment 2

[0024] The present embodiment adopts following proportioning and process step to realize:

[0025] a. Superfinely pulverize 25% of Shuanghua (honeysuckle), 15% of nasturtium, 25% of forsythia, 20% of Bupleurum bupleurum and filter through> 300 mesh fine sieve, put into the temperature of 55 ℃ After soaking in water for 2 hours, the medicinal solution is dynamically extracted by pump circulation, and the extracted medicinal solution is then dynamically soaked in water at a temperature of 60°C for 1.5 hours, then combined and decocted, filtered, and concentrated to relative After the density is 1.22 (measured at 80°C), slowly add ethanol when the medicinal solution is cooled to 35°C, and fully stir when the alcohol content reaches 70%. After standing for 14 hours, take the supernatant, Recover ethanol under reduced pressure until there is no alcohol smell, and set aside;

[0026] b. Slice 15% Scutellaria baicalensis, add water and decoct three times, the first time for 2 hours,...

Embodiment 3

[0029] This embodiment adopts the following proportions and process steps to realize: the advantage of this preparation method is that the active ingredients have high purity, it is easy to be in line with international standards, and it is easy to register and sell abroad, but the cost is relatively high.

[0030]a, decoct 25% of Shuanghua (honeysuckle), 20% of nasturtium, 20% of scutellaria, and 20% of forsythia by weight, and decoct 2 times, each time for 60 minutes, filter, then combine the filtrate and leave it for 12 hour; get the filtrate supernatant through the pre-treated colorless and clear macroporous resin column adsorption (flow velocity 5ml / min), discard the cleaning solution, then elute with 85% ethanol, when there is a yellow ethanol solution to flow out, Start to collect the eluate until it does not contain baicalin; then recover the ethanol and concentrate it to the fluid extract for later use;

[0031] b. Extract Bupleurum volatile oil: Put 15% (by weight) d...

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PUM

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Abstract

The present invention relates to a Chinese medicine Shuangjinlian oral liquor for curing common-cold and epidemic influenza and its preparation method. It is characterized by that the medicine is prepared by using (wt%) lonicera flower 10-40%, globeflower 10-25%, scutellaria root 10-25%, forsythia fruit 20-40% and bupleurum root 15-30%. The oral liquor possesses the advantages of high effective component contents, inhibiting several influenza viruses and several pathogenic bacteria, quick abatement of fever, stopping pain and relieving cough, etc.

Description

(1) Technical field: [0001] The invention relates to the field of medicine, in particular to a Shuangjinlian oral liquid for treating cold and flu and a preparation method thereof. (two) background technology: [0002] Influenza and colds are common, frequent and extremely harmful epidemic diseases to humans. The largest global influenza outbreak in history has caused more than 30 million deaths, equivalent to the death toll of World War I. The occurrence of influenza is mostly caused by influenza virus, but there are very few specific drugs for treating influenza virus in the world today. Most of the western medicines in the prior art are drugs for relieving symptoms, but amantadine, which can play a therapeutic role, cannot be popularized and used because of its high cost. Although the commonly used antipyretic and analgesic drugs can alleviate the symptoms of fever, pain, cough and other discomforts caused by the onset of the disease, they do not have a therapeutic effec...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P31/00A61P31/12
Inventor 邢泽田
Owner HENAN TALOPH PHARMACEUTICAL STOCK CO LTD
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