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Suppository for treating gynecopathy and its preparation technology

A technology for gynecological diseases and suppositories, which is applied in the field of medical suppositories and its preparation, which can solve the problems that drugs cannot act directly, affect the concentration of effective administration, and easily pollute clothes, etc., and achieve good vaginal efficacy, satisfactory curative effect, and no pollution to clothes.

Inactive Publication Date: 2005-10-26
贵州长生药业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The first is that the depth of entry into the vagina is not enough, and the drug cannot directly act on the lesion; the second is that part of the drug flows out after the drug enters the vagina and dissolves, which directly affects the effective administration concentration; the third is that the inflammatory secretions that flow out together with the drug can easily contaminate the clothes , creating new opportunities for infection

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0015] Embodiments of the present invention: taking the production of 1000 suppositories as an example, first get 642.9g of Sophora flavescens, 321.4g of Radix radiata, 321.4g of Fructus Cnidii, 321.4g of Agrimony, and 321.4g of Purple Pearl are processed through net selection, add water and decoct three times, Add 10 times of water for the first and second times, decoct for 2 hours, add 8 times of water for the third time, decoct for 1 hour, combine the decoction, filter and concentrate to an appropriate amount, add 95% ethanol, adjust the amount of ethanol to 30-35%, and let it stand Set aside to make precipitation, take the supernatant, filter, after the ethanol is recovered from the filtrate, it is concentrated to an extract with a relative density of 1.3-1.35 for later use; another 260g of glycerin and 950g of gelatin are used to prepare a glycerin-gelatin matrix, and then 60g of boric acid and 10g of alum are added in sequence , then add the medicinal extract, finally add...

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PUM

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Abstract

The suppository for treating women's diseases is prepared with flavescent sophora root, sessile stemona root, cnidium fruit, agrimonia herb, alkanna, alum, boric acid, borneol, camphor and glycerine-gelatin matrix. It has the advantages of being convenient and safe, sanitary, high treating effect, no secondary and no toxic side effect. After the suppository with sanitary cotton strip is pushed into deep vagina with a disposable pushing device, the cotton strip meeting body fluid will expand to block medicine flow out and the cotton strip may be taken out easily together with inflammatory secretion. The vagina is cleaned while producing no contamination to clothing. The present invention is one Chinese medicine preparation without toxic side effect.

Description

Technical field: [0001] The invention relates to a medical suppository and a preparation process thereof. technical background: [0002] Mycotic, trichomonas, bacterial nonspecific vaginitis, cervicitis, and cervical erosion are the most common diseases in women. Although there are many medicines for external use for the treatment of the above-mentioned diseases at present, the main dosage forms are aqueous preparations, common suppositories, tablets, capsules, powders, ointments, etc., but these dosage forms all have problems and deficiencies in varying degrees. The first is that the depth of entry into the vagina is not enough, and the drug cannot directly act on the lesion; the second is that part of the drug flows out after the drug enters the vagina and dissolves, which directly affects the effective administration concentration; the third is that the inflammatory secretions that flow out together with the drug can easily contaminate the clothes , resulting in new oppo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/02A61P15/02
Inventor 邓艳生
Owner 贵州长生药业有限责任公司
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