31 results about "Gelatin matrix" patented technology

A range of products and methods are based on a creamy base of cream, artificial cream, thickened cream, cream cheese, mixtures thereof and mixtures with compatible incidental ingredients, the creamy base being aerated while cold and intimately mixed with a hot aqueous gelatin solution typically around 80° C. and providing 1-3% gelatin in the mixed product and the overrun in the aeration being typically in the range of 10-40%. Various further components are included or introduced with further processing selected from methods including heating the product with a further component to boiling point whereby de-aeration and enhanced shelf life is found in the resultant product. An alternative method is where flavor components are added prior to de-aeration. Another application is as a carrier for a pharmaceutical agent which is incorporated into the creamy base and protected with the gelatin matrix, a powder being formed ready for packaging in pharmaceutical doses. Another embodiment which does not require heating is incorporating a flavoring agent and food acid to obtain a pH of 3.0 to 4.2 an adding a large volume of water which has the effect of ensuring a low viscosity and the elimination of aeration whereby a pourable sauce-like product can be achieved at refrigeration temperatures.

The present invention relates to particulate compositions comprising controlled release particles wherein discrete elements of flavouring-containing fat are dispersed in a gelatine matrix, said particles containing: 0.1-40 wt%, preferably 5-30 wt% of flavouring; 10-70 wt%, preferably 20-50 wt% of gelatine; and 0.1-75 wt%, preferably 5-50 wt% of fat, the fat having a melting point of at least 35 DEG C; and said particles having a volume weighted average diameter of 50 - 1500 m. The particulate composition according to the present invention will release the flavouring comprised therein under specific conditions e.g. under the influence of shear forces, heat and / or moisture. The release rate upon consumption can be affected by varying the relative amounts of gelatine and fat and the gelling strength of the gelatine. These compositions are therefore particularly suitable for imparting longer lasting taste sensation to confectioneries, in particular chewing gume, and to toothpaste.

The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix is a lyophilized mixture of protein(s), polymer(s), cross-linking agent(s) and optional plasticizer(s). The invention also provides methods for making the non-adhesive elastic gelatin matrix.

The invention relates to the field of pharmacology. More specific, the invention relates to a controlled release composition.This invention is related to a controlled release composition comprising a cross-linked gelatin and at least one therapeutic protein wherein the ratio of the average mesh size (ξ) of the gelatin matrix and the average hydrodynamic radius (RH) of the therapeutic protein is smaller than 2, preferably smaller than 1.5.

Bisphosphonates inhibit bone resorption associated with periodonatal or orthopedic surgery when applied topically to the bone. A novel formulation for topical application contains a gelatin matrix which is soaked in a solution containing a bone absorption inhibiting effective amount of a bisphosphonate or a pharmaceutically acceptable salt.

The invention discloses a chromium-containing gelatin standard substance and a preparation method thereof. The standard substance takes gelatin as a matrix, and chromium is added into the gelatin so that the chromium content of the standard substance is 10mg / kg. The chromium-containing gelatin standard substance and preparation method thereof disclosed by the invention have the following advantages and beneficial effects that: based on a characteristic that the gelatin is insoluble in clod water and soluble in warm water, trace of chromium is added into the gelatin matrix, so that the standard substance for detecting the chromium content of the gelatin is formed; the application of the standard substance facilitates the improvement of the matching degree of the standard substance and the sample matrix in the detection of the chromium content of the gelatin, thereby improving the accuracy and reliability of detection results. The preparation method of the standard substance is simple to operate and easy to promote, and the chromium content of the prepared gelatin standard substance is uniform.

The invention relates to a method for preparing graphene oxide based on gelatin, and application thereof, and belongs to the technical field of graphene oxide. The technical problem that the method for preparing the graphene oxide in the prior art is unsafe, complex in process flow and high in cost is solved. The preparation method comprises the following steps: dissolving gelatin with solvent, and filtering to remove impurity to obtain a gelatin solution; volatizing the solvent in the gelatin solution to obtain a gelatin matrix in a fixed shape; and performing high-temperature carbonization treatment on the gelatin matrix in the fixed shape under the protection of the inert gas atmosphere protection, and cooling to room temperature to obtain graphene oxide. The preparation method takes biomass as a precursor to prepare the graphene oxide, the raw material is rich in resource, cheap and easy to obtain, pollution-free and renewable; and meanwhile, the method is safe and controllable inprocess, simple in flow and easy to operate.

A chewing gum product containing a cross-linked gelatin matrix gum base and a bulking agent of erythritol, mannitol, or mixtures thereof. The cross-linked gelatin matrix can make up all or a portion of the gum base and still be comparable to that of a traditional elastomeric chewing gum product in its elasticity, cohesiveness, and feel in the mouth. The chewing gum of the present invention is also more environmentally friendly because it can be digestible and partially replace the need for petroleum-derived elastomers.

The invention relates to an agarose crystal gel matrix particle with extra large pores and a preparation method thereof. The agarose crystal gel matrix particle is characterized in that the super-pore agarose crystal gel matrix particle is a porous particle, and has the super pore of tens to hundreds of microns, the particle size of 2-5mm, the pore diameter of 5-200 micrometers and the porosity of 94-97 percent. The invention also provides a method for preparing the agarose crystal gel matrix particle by multi-micropipe reactor droplet forming and solvent crystallization hole forming. The agarose crystal gel matrix particle has good biocompatibility and the mutually communicated extra large pores, is high in porosity, excellent in permeability, and easy for realizing in-pore convective mass transfer of target objects, and therefore can serve as base materials of carriers for immobilization and biological separation media. The preparation method is simple, parallel amplification can be realized, large-scale industrial preparation is convenient, and the agarose crystal gel matrix particle with the extra large pores and the preparation method thereof have wide application prospect in the fields of biological separation, tissue engineering, immobilization of enzymes or cells, and the like.

The suppository for treating women's diseases is prepared with flavescent sophora root, sessile stemona root, cnidium fruit, agrimonia herb, alkanna, alum, boric acid, borneol, camphor and glycerine-gelatin matrix. It has the advantages of being convenient and safe, sanitary, high treating effect, no secondary and no toxic side effect. After the suppository with sanitary cotton strip is pushed into deep vagina with a disposable pushing device, the cotton strip meeting body fluid will expand to block medicine flow out and the cotton strip may be taken out easily together with inflammatory secretion. The vagina is cleaned while producing no contamination to clothing. The present invention is one Chinese medicine preparation without toxic side effect.

The invention provides a preparation method of microgel for delivering adipose-derived stem cells, which comprises the following steps: completely dissolving methacryloyl gelatin and a photoinitiator phenyl-2, 4, 6-trimethylbenzoyl lithium phosphonate in phosphate buffer normal saline to obtain a gelatin matrix; taking adipose-derived stem cells transferred to the third generation or after the third generation in the logarithmic phase, putting the adipose-derived stem cells into the gelatin matrix, and enabling the adipose-derived stem cells to suspend in the gelatin matrix; and printing the gelatin matrix mixed with the adipose-derived stem cells by using DLP-3D printing equipment to obtain the microgel carrying the adipose-derived stem cells. According to the prepared microgel bearing the adipose-derived stem cells, the adipose-derived stem cells are evenly distributed in the microgel, the adipose-derived stem cells are basically spherical in the microgel, damage to the adipose-derived stem cells is small, and survival of the adipose-derived stem cells is facilitated. The biocompatibility is good, and the adipose-derived stem cells have no adverse reaction. The microgel contributes to in-vitro adipogenic differentiation of the adipose-derived stem cells, promotes proliferation of the adipose-derived stem cells, and can support in-vitro 3D culture of the adipose-derived stem cells.

The invention discloses a preparation method of a gelatin-based food packaging film, which comprises the following process steps: 1) mixing and soaking 16-30 parts of gelatin and 100 parts of distilled water according to the mass parts of raw materials for 0.5-1.5 hours to obtain a gelatin matrix; 2. ) Add 15 to 25 parts of an aqueous solution of a titanium compound with a concentration of 3 to 10 g / L into the gelatin matrix, then add 15 to 25 parts of an aqueous solution of high-polymerization flavanols with a concentration of 0.5 to 2 g / L, and then add 3 to 6 parts of aqueous sodium hydroxide solution with a concentration of 0.1-1.2 mol / L and 3-6 parts of glycerin are cast into a film and dried to obtain a finished product. The present invention uses natural polyflavanol and high-safety titanium ion as a composite crosslinking agent, utilizes the principle that protein reactive sites increase after the coordination compound is formed by titanium ion and polyflavanol, and prepares high-safety Gelatin-based food packaging film with excellent physical and mechanical properties.

The invention relates to a method and application for preparing graphene oxide based on gelatin, and belongs to the technical field of graphene oxide. The method solves technical problems such as unsafe factors, complicated process flow and high cost in the method for preparing graphene oxide in the prior art. The preparation method of the present invention first dissolves the gelatin with a solvent, filters to remove impurities, and obtains a gelatin solution; then volatilizes the solvent in the gelatin solution to obtain a gelatin matrix in a fixed form; and then protects the gelatin matrix in a fixed form under the protection of an inert gas atmosphere Carry out high-temperature carbonization treatment, cool to room temperature, and obtain graphene oxide. The preparation method uses biomass as a precursor to prepare graphene oxide, and the raw material resources are abundant, cheap and easy to obtain, pollution-free and renewable, and at the same time, the method has safe and controllable process, simple process and easy operation.

The invention discloses a chromium-containing gelatin standard substance and a preparation method thereof. The standard substance takes gelatin as a matrix, and chromium is added into the gelatin so that the chromium content of the standard substance is 10mg / kg. The chromium-containing gelatin standard substance and preparation method thereof disclosed by the invention have the following advantages and beneficial effects that: based on a characteristic that the gelatin is insoluble in clod water and soluble in warm water, trace of chromium is added into the gelatin matrix, so that the standard substance for detecting the chromium content of the gelatin is formed; the application of the standard substance facilitates the improvement of the matching degree of the standard substance and the sample matrix in the detection of the chromium content of the gelatin, thereby improving the accuracy and reliability of detection results. The preparation method of the standard substance is simple to operate and easy to promote, and the chromium content of the prepared gelatin standard substance is uniform.