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Multi-function health care food and application thereof

A technology of insulin resistance and extract, applied in the field of lotus root extract in the pharmaceutical field, can solve the problem of complex pathogenesis

Inactive Publication Date: 2006-03-22
YUNNAN BAIYAO GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the pathogenesis of IR is complex, involving defects in pre-Ins receptors, receptors, and post-receptors at different levels and in different links
So far, there is still a lack of a safe and effective drug that can comprehensively improve IR and its related disease groups

Method used

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  • Multi-function health care food and application thereof
  • Multi-function health care food and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] -Effect of lotus root joints on rat model of nutritional obesity

[0022] 1.1 Materials and methods

[0023] 1.1.1 Preparation of experimental materials and feed

[0024] (1) Test materials Wash and dry lotus root joints and lotus root buds respectively, and then place them in an oven at 65°C for blast drying, and use a pulverizer to make fine powders for use on the same day.

[0025] Preparation of lotus root dregs: wash and mash fresh lotus root, soak in clean water and stir to remove starch, then fish out, wrap with gauze to squeeze out the water in the dregs, dry and make fine powder under the same conditions as above, and prepare for the same day use.

[0026] (2) Positive drug Ninghong Slimming Tea (produced by Jiangxi Ninghong Group Company, batch number: 20011102.) was crushed into fine powder for use on the same day.

[0027] (3) Experimental feed

[0028] Concentrated high-calorie feed: 40% basic feed, 35% lard, 15% sucrose, 8% eggs, 2% salt.

[0029] Exp...

Embodiment 2

[0060] -Effect of lotus root extract on nutritionally obese rats

[0061] 2.1 Materials and methods

[0062] 2.1.1 Drugs and their preparation

[0063] Lotus root decoction extract: Take an appropriate amount of dried lotus root, crush it to the size of soybeans, add 6 to 10 times the amount of water, heat to boil, decoct on low heat for 30 to 40 minutes, filter while it is hot, and remove the dregs like this Extract once, combine the extracts, concentrate under reduced pressure, dry in vacuum, water content 6%, keep in a sealed container for future use

[0064] Ethanol reflux extract of lotus root: Take an appropriate amount of dried lotus root, crush it to 20 mesh particles, add 6 to 10 times the amount of 30% to 90% ethanol, heat and reflux in a water bath for 1 hour, filter while it is hot, and extract the dregs again in this way, Combine extracts, concentrate under reduced pressure, reclaim ethanol, vacuum dry, water content 5%, seal preservation, sex difference; Compar...

Embodiment 3

[0072] -Effect of lotus root composition on nutritionally obese rats

[0073] 3.1 Materials and methods

[0074] 3.1.1 Drugs ① cold-dried lotus root extract cold-dried powder (preparation method as in experiment 2); 1 >30%, Rg 1 >20%; Notoginseng saponin: aglycone containing 32% based on protopanaxadiol); ③green tea extract (tea polyphenols 40%, catechin 25%, EGCG 25%, caffeine <5%) for later use .

[0075] Ethanol cold soak extract of lotus root: take an appropriate amount of dried lotus root, crush it to 20 mesh particles, add 6-10 times the amount of 30%-90% ethanol, soak at room temperature for 24 hours, filter, and add the above concentration to the dregs Ethanol, extracted twice in this way, combined extracts, concentrated under reduced pressure at low temperature, recovered ethanol, dried in vacuum, with a water content of 5%, sealed and stored for future use.

[0076] Lotus root herb powder: the preparation method is the same as in Example 1.

[0077] 2.1.2 Animal...

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Abstract

The multifunctional health-care food is an extract of lotus root node or lotus root node composite. The composition of the described lotus root node composite contains (by weight portion) 4-7.5 portions of lotus root node extract, 4-15 portions of lotus root node powder, 1-1.5 portions of green tea extract and 1 portions of notoginseng extract. The above-mentioned all the components are uniformly mixed, made into fine granules, and the beta-cyclodextrin inclusion compound of cinnamon volatile oil is added, uniformly mixed and capsulized so as to obtain the invented product. It can effective improve IR, and can prevent diabetes II type, hypertension, hyperlipidemia and cardio-cerebral vascular diseases, and possesses the function of reducing weight.

Description

technical field [0001] The invention relates to a lotus root extract, more specifically, the invention relates to the application of the lotus root extract in the field of pharmacy. Background technique [0002] With the continuous improvement of living standards and changes in lifestyle, the incidence of obesity, type 2 diabetes, hypertension, hyperlipidemia, and cardiovascular and cerebrovascular diseases is increasing, and these diseases often coexist, resulting in a high mortality and disability rate. It is a major disease that threatens human health today. A large number of studies at home and abroad in the past ten years have shown that the above-mentioned diseases have a common pathogenic basis, that is, insulin resistance (abbreviated as -IR). IR is the central link of the above-mentioned disease group, and obesity is the prelude to several other diseases. The so-called IR refers to the normal or higher than normal level of insulin (Ins) in the blood, which can only...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/62A61P3/06A61P3/10A61P9/12A61P7/02A61P25/28A23L1/30A23L33/00A61K9/08A61K9/14A61K9/19A61K9/20A61K9/48A61K36/00A61K36/18A61P3/04A61P7/00
CPCA61K36/48A61P25/28A61P3/10A61P3/04A61P3/06A61P7/00A61P7/02A61P9/12
Inventor 潘玲李德良张立群唐文旭杨成金高崇昆冯友陈勉
Owner YUNNAN BAIYAO GROUP