Polymer microsphere encoded by nano-gold and method for preparing same

Abstract

A polymer microsphere encoded by nano-gold particles and a preparation method thereof, relating to a polymer microsphere that can be used as a high-throughput carrier for multiple biological analysis and protein, gene, and drug screening. The microsphere is composed of ethylene polymer and Nano-gold particles, wherein: the content of nano-gold particles in polymer microspheres is 1.42-33.3‰, and the ethylene polymer is polystyrene, or polymethyl methacrylate, or polyacrylonitrile, or polyethylene, or poly Acrylic, or polyethyl acrylate. The preparation method comprises the following steps: dissolving ethylene polymer in an organic solvent to form an ethylene polymer solution, dropping the ethylene polymer solution into a polyvinyl alcohol solution through a droplet generating device, and obtaining polymer microspheres after the organic solvent is volatilized.

Description

technical field

[0001] The invention relates to a polymer microsphere that can be used as a high-throughput carrier for multiple biological analysis and protein, gene, and drug screening, in particular to a polymer microsphere encoded by nano gold and a preparation method thereof. Background technique

[0002] After the human genome sequence was decoded, the function of the gene and the interaction between the proteins encoded by the gene became a research hotspot, and human beings entered the post-genome era. A notable feature of the post-genome era is to study a large number of interactions between proteins and nucleic acids, proteins and proteins, and proteins and drugs. The study of these interactions is almost impossible with traditional experimental methods. Therefore, a high-throughput test platform is needed. The high-throughput test platform requires a high-throughput molecular carrier to identify the different interactions of different molecules, which is the so-c...

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