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Motherwort dropping pill and its preparing method

A technology of grass dripping pills and motherwort, which is applied in the direction of pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of long dissolution time, heavy financial burden on patients, and low dissolution rate, so as to avoid gastrointestinal Tract irritation symptoms, enhanced bioavailability, accelerated dissolution and absorption

Inactive Publication Date: 2007-05-16
广西宝瑞坦广明制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Due to the limitation of existing injection preparation technology and the influence of the complexity of traditional Chinese medicine ingredients, traditional Chinese medicine injections are often prone to acute allergic reactions or adverse reactions, and there are also difficulties in operation, great pain for patients, high manufacturing and medical costs, and inconvenient transportation and storage. , heavy financial burden for patients, unsuitable for family use and other disadvantages
[0007] In addition, due to preparation technology and other reasons, most oral preparations of drugs have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking, which affect the drug efficacy. The play also directly affects the therapeutic effect
At the same time, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0029] Now with several groups of specific examples, the preparation method of motherwort dripping pills of the present invention will be further described.

[0030] [Group 1: Trials with a single substrate]

[0031] 1. Raw materials: according to the preparation method 1, the dry powder containing the active pharmaceutical ingredients of the traditional Chinese medicine Motherwort is pre-prepared for use;

[0032] 2. Substrate: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0033] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0034] 4. Prepare according to the process given in [Preparation Method] 4-7, and you can get motherwort dripping pills with different specifications.

[0035] [test results]

[0036] Experiment ...

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PUM

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Abstract

The present invention discloses a Chinese medicine composition with the action of contracting uterine for regulating menstruation and arresting hemorrhage. Said medicine composition can be made into oral Yimucao dripping pills, and is made up by using Chinese medicinal material motherwort as raw material and medicinal carrier as matrix through a certain preparation proves.

Description

technical field [0001] The invention relates to a pharmaceutical composition for gynecological hemostasis and menstruation regulation with the effect of contracting the uterus, in particular to an oral preparation of the pharmaceutical composition prepared from the traditional Chinese medicine Motherwort as a raw material and a pharmaceutically acceptable carrier as a matrix. Background technique [0002] According to the drug standard WS issued by the national ministry 3 - Motherwort injection prepared according to the formula and extraction process given in B-3969-98 is a pure traditional Chinese medicine injection for gynecological hemostasis and regulating menstruation. It has been clinically verified for many years, with stable quality and definite curative effect. It is clinically and Common medicines used at home to treat the above diseases. [0003] The following is the drug standard WS 3 -Recipe and extraction process given in B-3969-98: [0004] Preparation meth...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/533A61P15/00A61P7/04
Inventor 曲韵智
Owner 广西宝瑞坦广明制药有限公司
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