Test strip device with lid-provided pretreatment portion

A test device and pretreatment technology, applied in measuring devices, sampling devices, biological testing, etc., can solve the problems of inability to coagulate and centrifugal separation, time-consuming, etc.

Inactive Publication Date: 2002-11-27
MEDIX BIOCHEMICA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The test device is used in first aid, especially in ambulances, where coagulation and centrifugation are not possible or are too time-consuming

Method used

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  • Test strip device with lid-provided pretreatment portion
  • Test strip device with lid-provided pretreatment portion
  • Test strip device with lid-provided pretreatment portion

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0071] Whole blood rapid test for iron-deficiency anemia (IDA) risk in pregnancy

[0072] The serum ferritin concentration shows how much iron is in the body. Ferritin is an early marker of iron-deficiency anemia (IDA) because ferritin concentrations decrease before anemia develops. Pre-latent and latent anemia can be detected before a decrease in hemoglobin concentration is observable.

[0073] During pregnancy, serum ferritin decreases as the time of delivery approaches. Assessment of ferritin in the first trimester can be used to predict the risk of IDA in the second trimester.

[0074] The rapid test described below to determine ferritin can be used to estimate the need for iron supplementation during pregnancy.

[0075] The test is performed on whole blood. The break-off value is about 40 μg / l (calibrated according to the third international standard of the World Health Organization, code 94 / 572). A positive test result indicates that the risk of IDA during pregnancy...

example 2

[0082] Rapid test for the presence of environmental pollution

[0083] Collect environmental fungal assay samples, such as Stachybotrys chartarum assay samples, from suitable sites identified by the investigator as adequately representative of the contaminated area. Collect samples from locations including building materials, other substrates, dust accumulations, etc. Place the sample in a test tube containing buffer and shake carefully. The sample suspension is then placed into a test device. The test device consists of an immunochromatographic test stick for identifying Stachybotrys chartarum and a pretreatment device. Two pads of porous material were placed into the plastic chamber when assembling the pretreatment unit with a lid. The first pad is saturated with a reagent capable of precipitating cellular antigenic components from the fungal cell wall. The second pad consists of a filter material capable of filtering out large particles of fungal structures. If desired...

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PUM

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Abstract

The invention relates to a test device, which has a pretreatment part covered by a cover (2) having a hole (3) and connected by a hinge (A). The pretreatment part is mounted on the same base (1) as a test strip (not shown). In the lid (2) and the lid of the base are devices (7, 8 and 9) for supporting, fastening and fixing the pretreatment layers, forming excess liquid collection chambers (6), and controlling the flow of sample solutions and diluents. The test device is used in field tests and clinical methods, especially in emergency situations where fast results are required (Fig. 8).

Description

field of invention [0001] The present invention relates to a test device having a covered preconditioning section mounted on the same base as the test strip and having means for controllably normalizing the flow of sample and dilution fluid. Also disclosed is a method of using the test device to directly measure a sample that generally requires more or less time for a pretreatment procedure. Background of the invention [0002] Some biological samples, especially those obtained from whole blood, serum, urine, feces, saliva, sputum, synovial fluid, etc., need to be pretreated for diagnosis, including particle removal, agglutination, Chemical treatment, release of special components, immune capture, etc. [0003] Typically, a whole blood sample is clotted and centrifuged to separate blood cells and other disturbing or confounding elements before testing is performed. A number of novel, rapid clinical tests have been developed which are very satisfa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/10G01N33/48G01N33/53G01N33/543
CPCG01N33/54386
Inventor E·H·斯文斯
Owner MEDIX BIOCHEMICA
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