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Electrochemical sensor for determining dopamine

An electrochemical and sensor technology, applied in the field of electrochemical sensors, can solve problems such as the difficulty of electrochemical sensors, and achieve the effect of high selectivity and sensitivity

Inactive Publication Date: 2003-02-05
WUHAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Because carbon nanotubes are very stable and insoluble in water and general organic solvents, it is very difficult to directly use them in the preparation of electrochemical sensors.

Method used

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  • Electrochemical sensor for determining dopamine
  • Electrochemical sensor for determining dopamine
  • Electrochemical sensor for determining dopamine

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Experimental program
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Embodiment Construction

[0013] see figure 1 , the electrochemical sensor of the present invention comprises glassy carbon electrode 1, and glassy carbon electrode 1 is made of glassy carbon substrate 3, electrode lead 4 and insulating layer 5 that are electrically connected with glassy carbon substrate 3, and glassy carbon substrate 3 surface is coated with sensitive film 2. The sensitive membrane 2 is obtained by the following method: carbon nanotubes and cation exchange polymer Nafion (produced by DuPont, USA) are added to absolute ethanol, so that the content of carbon nanotubes is 0.1% to 15% (mass volume percentage, the same below) , The content of cation exchange polymer Nafion is 0.01% ~ 5%, and then ultrasonically dispersed until a uniform, light black carbon nanotube-cation exchange polymer Nafion dispersion is obtained, and the carbon nanotube-cation exchange polymer Nafion dispersion is coated Cover the surface of the glassy carbon electrode, and evaporate the solvent at low temperature (...

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Abstract

The invented electrochemistry sensor for measuring dopamine includes the glass-carbon electrode whose surface is coated with the sensing film composed of nano carbon tubes-Nafion of polymer of cation exchange. The Nafion of polymer of cation exchange is as the dispersant in the invention. The very stable nano carbon tubes can easily be dispersed in ethanol by the dispersant. The sensing film is prepared by coating the dispersant on the surface of the glass-carbon electrode. The dopamine is measured with high selectivity and sensitivity by using the electrochemistry sensor composed of the sensing film and the glass-carbon electrode. Even both of ascorbic acid and uric acid with high concentration are existed in the dopamine with low concentration, the electrochemistry snesor still gives the selective response.

Description

technical field [0001] The invention relates to an electrochemical sensor for measuring dopamine. Background technique [0002] Dopamine is an important neurotransmitter in the human body, which is involved in many life processes. Studies have shown that the occurrence of Parkinson's disease is closely related to the concentration of dopamine in the body. It can be seen that it is very important to detect the level of dopamine in the body. Electroanalytical chemistry is widely used in the direct electrochemical detection of living substances due to its advantages of high sensitivity, good selectivity, short response time, and low cost of required instruments and equipment. However, the electrochemical properties of substances such as high-concentration ascorbic acid (AA) and uric acid (UA) coexisting in the human body are very similar to dopamine, and they will have irresistible effects when measuring dopamine with general electrochemical methods. The development of electr...

Claims

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Application Information

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IPC IPC(8): G01N27/30G01N27/31
Inventor 胡胜水吴康兵孙延一
Owner WUHAN UNIV
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