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Health food capable of increasing bone density and delaying senility and its production process

A technology to increase bone density and soybeans, applied in food preparation, food ingredients, food ingredients containing natural extracts, etc., can solve the problems of increasing the incidence of endometrial cancer and breast cancer, and achieve the goal of ensuring reliability and stability Effect

Inactive Publication Date: 2003-05-14
SHANGHAI MODERN CHINESE TRADITIONAL MEDICINE TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, many studies have shown that the use of estrogen replacement therapy can significantly increase the incidence of endometrial cancer and breast cancer, so it is not a very ideal treatment method

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1 The experiment of the effect of health food of the present invention on increasing bone density

[0038] Sample properties and processing: The sample is a pink coated tablet, the tablet core is brown powder, the recommended dose for the human body is 3.6g / 60kg body weight per day, and the experiment has three dose groups: low, medium and high: each group is 0.30g, 0.60g, 1.80g / kg, equivalent to 5 times, 10 times, 30 times of the recommended human dose. At the same time, three control groups were set up: sham operation group, model control group, and positive control group.

[0039] Experimental animals: Wistar rats, female, weighing 220-250 grams.

[0040] Dosage design: The samples were divided into three dosage groups: low, medium and high. Add 0.30g, 0.60g and 1.80g of samples to 10ml deionized water respectively, and give 10ml / kg.bw to the stomach every day.

[0041] experimental method

[0042] 1. Ovariectomy: Rats were intraperitoneally injected wi...

Embodiment 2

[0060] Embodiment 2 The experiment of prolonging aging effect of health food of the present invention

[0061] A. Drosophila survival test

[0062] Sample: It is a pink coated tablet, and the tablet core is a tan powder.

[0063] Test animal: Oregon K wild-type Drosophila melanogaster

[0064] Dosage grouping: According to the recommended human dose (3.6 g / person·day), a blank control group and 4 dosage groups were established, and the concentrations of samples contained in the culture medium of each dosage group were: 0.01%, 0.04%, 0.12% and 0.36%.

[0065] Test method: collect newly eclosioned fruit fly adults within 8 hours, divide male and female into random groups under ether anesthesia, and carry out the test after weighing them separately. Each group uses 400 fruit flies, half male and half male. The control group was given common corn flour culture medium; the test group was given culture medium containing 0.01%, 0.04%, 0.12% and 0.36% of the sample respectively. ...

Embodiment 3

[0081] Embodiment 3 The preparation of health food of the present invention

[0082] 1. Weigh 250 grams of Angelica crude drug, mechanically pulverize it, and sieve it to 20 mesh. The obtained powder is prepared by supercritical CO 2 Extraction process for extraction, the powder is placed in supercritical CO 2 Extraction tank, the extraction pressure is 10Mpa, the extraction temperature is 40°C, and then 0.75 grams of angelica oil is separated in the separation tank, for standby, the separation pressure is 1Mpa, the separation temperature is 20°C, and the liquid CO 2 The flow rate is 25Nm 3 / h, recycle in the process for extraction, the extraction time is 2 hours, take out 249 grams of angelica powder after oil extraction from the extraction tank, and set aside;

[0083] 2. Weigh 1 kg of soybeans, grind them mechanically, and sieve through 20 meshes. The obtained soybean powder is degreased with n-hexane, dried, and removed from the solvent. Extract with 80% ethanol, concen...

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PUM

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Abstract

The health food capable of increasing bone density and delaying senility consists of the effective components of soybean, epimedium, astragalus root, angelica and mulberry as well as supplementary material including calcium gluconate, carboxymethyl starch sodium and avicel. The preparation process of the health food includes supercritical CO2 extraction to obtain angelica oil; ethanol extraction to obtain soybean isoflavone; water extraction of epimedium, astragalus root, mulberry and angelica after extracting oil, spray drying and other steps to prepare powder; mixing soybean isoflavone and the powder as well as calcium gluconate, carboxymethyl starch sodium and avicel; pelletizing, tableting and coating to obtain the health food product.

Description

technical field [0001] The invention relates to a health food for increasing bone density and delaying aging, and relates to a health food for increasing bone density and delaying aging which is mainly made of medicinal and edible raw materials and a preparation method thereof. Background technique [0002] Aging is a natural development process of body tissue structure changes and functional decline with age. With the aging of the human body, the bone metabolism of the body will also be disordered, and the balance between the actions of osteoblasts and osteoclasts will be broken. Bone resorption is greater than bone formation, resulting in decreased bone mass, decreased bone density, and eventually osteoporosis. Low back pain, spinal deformity, and easy fractures have seriously affected people's quality of life. Decreased bone density and osteoporosis are particularly serious in postmenopausal elderly women, with a prevalence rate as high as about 50%. There are no good t...

Claims

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Application Information

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IPC IPC(8): A23L11/00A23L33/105A61K36/232A61K36/296A61K36/48A61K36/481A61P19/10A61P39/06
CPCA23V2002/00A61K36/48A61K36/232A61K36/296A61K36/481A23L1/2006A23L1/3002A23L11/07A23L33/105A61P19/10A61P39/06A23V2250/2116A23V2250/21
Inventor 王成荣王丽芬
Owner SHANGHAI MODERN CHINESE TRADITIONAL MEDICINE TECH DEV
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