Application of acetyl boswellic acid in preparing antitumor agent

A technology of boswellic acid and anti-tumor drugs, which can be applied in the directions of anti-tumor drugs, medical preparations containing active ingredients, organic active ingredients, etc., and can solve problems such as limiting the therapeutic effect of malignant tumors and toxic and side effects
CN1436533AInactive Publication Date: 2003-08-20INST OF MATERIA MEDICA CHINESE ACAD OF MEDICAL SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF MATERIA MEDICA CHINESE ACAD OF MEDICAL SCI
Publication Date
2003-08-20
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention is the application of acetyl boswellic acid (BC-4) extracted from Boswellia carterii Birdw as antitumor medicine, a secondary application. It is found that BC-4 has the functions of resisting the proliferation of tumor cell, inducing malignant tumor cell to death, inhibiting the proliferation of human umbilical vein endothelial cell, inhibiting animal's grafted tumor, inhibiting metastasis of malignant tumor, etc. Both in vivo and vitro tests show that BC-4 has very low toxicity and is one excellent antitumor medicine and tumor metastasis inhibitor.
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Description

technical field

[0001] The invention relates to a new application of pentacyclic triterpenes extracted from the traditional Chinese medicine frankincense, acetylboswellic acid (BC-4) in the preparation of antitumor agents, that is, the second use of the medicine. Background technique

[0002] Cancer is a serious threat to human life. The combination of surgery, radiotherapy and chemotherapy has successfully improved the cure rate of various malignant tumors and reduced the mortality of cancer patients. However, many factors, such as tumor invasion and metastasis and resulting recurrence after treatment, strong toxic and side effects of anticancer drugs, and drug resistance of cancer cells, still limit the therapeutic effect of malignant tumors. The behavior of invasion and metastasis is the most essential characteristic of malignant tumors, and it is also the crux of the lethality of malignant tumors. Preventing the invasion and metastasis of carcinoma in situ with chemical...

Claims

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