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Granule of ÔÇÿJingangtengÔÇÖ for treating inflammatory gynecopathy and its preparation method

A technology for gynecological inflammation and granules is applied in the field of traditional Chinese medicine preparations for treating gynecological inflammatory diseases and the preparation thereof, which can solve the problems such as unreported, inconspicuous pharmacological effects, inconvenient transportation and carrying, etc. Easy to transport, take and carry, long-lasting effect

Inactive Publication Date: 2003-10-08
陕西海天制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the syrup also has many deficiencies in actual use, such as inconspicuous pharmacological effects, large doses, difficult preservation, inconvenient transportation, etc.
Due to the lack of research on the chemical composition, pharmacological effects and new dosage forms of King Kongteng in the past, and the limitation of the use route and some other factors, the development of other dosage forms of King Kongteng medicine has not been reported so far.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Take 3000g of Vajra vine, add water and decoct three times, 1 hour each time, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.05. Add ethanol to make the ethanol content in the solution 40%. Let stand for 24 hours and filter. , The filtrate recovers ethanol and concentrates it to a clear ointment with a relative density of about 1.20 (heated at 60°C); take 1 part of the clear ointment, 4 parts of sucrose, 1 part of dextrin, mix, make granules, dry, and pack, ready to make The sugar-containing soluble granules of the present invention are obtained.

Embodiment 2

[0020] Take 3000g of Vajra vine, add water and decoct 2 times for 1.5 hours each time, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.10. Add ethanol to make the ethanol content in the solution 45%. Let stand for 36 hours. After the filtration, the ethanol is recovered from the filtrate and concentrated to a clear ointment with a relative density of about 1.22 (thermally measured at 60°C); take 1 part of the clear ointment, 5 parts of dextrin, and 0.035 parts of stevioside, mix them, dry them into granules, and pack them. The sugar-free soluble granules of the present invention are prepared.

Embodiment 3

[0022] (1) Take 4320g of King Kong Vine, take out 3800g of it, add 6 times the amount of 70% ethanol and soak for 15 hours, heat and reflux for extraction 2 times, 2.5 hours each time, combine the extracts, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.18 (60℃) thick paste.

[0023] (2) Take the above thick paste, dry it in vacuum at 50-60°C, and pulverize it into fine powder.

[0024] (3) Take the remaining amount of diamond vine in the above step (1), pulverize it into fine powder, mix it with the fine powder obtained in the above step (2), granulate, dry, size, and package to obtain the sugar-free of the present invention Suspended granules.

[0025] The present invention provides a natural medicine for the treatment of gynecological inflammatory diseases. In order to prove its therapeutic effect and safety, the inventors conducted toxicological and pharmacodynamic tests using the granules prepared according to the method provided in Exa...

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PUM

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Abstract

A Chinese medicine in the form of particles for treating gynecologic inflammation, such as annexitis, is prepared from bock greenbrier rhizome. Its preparing process is also disclosed. Its advantage is sure curative effect.

Description

Technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, and relates to a Chinese patent medicine preparation for treating gynecological inflammatory diseases and a preparation method thereof. Background technique [0002] Gynecological inflammatory diseases such as adnexitis, adnexa inflammatory mass, etc. are common and frequently-occurring diseases in clinical practice. At present, there are many drugs used to prevent and treat gynecological inflammatory diseases in this field, especially some traditional Chinese medicine preparations in clinical practice. In practice, quite unique curative advantages have also been formed. However, due to the high incidence of gynecological inflammatory diseases and complicated pathological mechanisms, some existing pharmaceutical preparations cannot yet fully meet the needs of clinical and market conditions, and research institutions and The staff made further explorations to develop more ideal new ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/10A61K9/16A61P15/00A61P29/00
Inventor 王春王宇张国莹王辉
Owner 陕西海天制药有限公司
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