Huanglian Shangqing Granule and preparation method thereof

A technology of Coptis chinensis and supernatant, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and bulk delivery, etc., can solve the problems that the active ingredients cannot be fully extracted and the efficacy of the drug is not good, so as to improve the pharmacological properties and improve the administration efficiency. Convenient and effective results

Inactive Publication Date: 2004-11-10
重庆东方药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The existing Coptis chinensis supernatant product usually adopts the production step of crushing the drug and directly roughing it. The active ingredients cannot be fully extracted, and the drug effect is not good.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Coptidis 24 grams Forsythia 144 grams Nepeta ear 144 grams Ginger gardenia 144 grams

[0020] Angelica dahurica 144g, chrysanthemum 360g, mint 48g, wine fried cork 48g

[0021] Chuanxiong 48g Gypsum 48g Scutellaria baicalensis 144g Wine-roasted rhubarb 720g

[0022] Fangfeng 48g Platycodon grandiflorum 144g Inula 48g Stir-fried vitex 144g

[0023] Licorice 48g

[0024] Its manufacturing method is:

[0025] a. Grinding 60% rhubarb, rhubarb rhubarb, phellodendron phellodendron, and angelica dahurica into fine powder, sieved, and mixed;

[0026] b. Use 6 times the amount of 70% ethanol to percolate the remaining thick head, windproof, platycodon grandiflorum, and remaining rhubarb after being crushed and sieved in a, collect the filtrate, and reclaim ethanol;

[0027] c. Extract volatile oil from nepeta, mint and chuanxiong, and collect the distilled aqueous solution in another device;

[0028] d. Decoct the medicinal residues in step c with Inula inulae, Forsythia, G...

Embodiment 2

[0030] Coptidis 24 grams Forsythia 192 grams Nepeta ear 192 grams Ginger Gardenia 192 grams

[0031] Angelica dahurica 192g, chrysanthemum 384g, mint 96g, wine fried cork 96g

[0032] Chuanxiong 96g Gypsum 96g Scutellaria baicalensis 192g Wine-roasted rhubarb 768g

[0033] Fangfeng 96g, Campanulaceae 192g, Inulae 48g, Stir-fried Vitex 192g

[0034] 96 grams of licorice, its manufacture method is:

[0035] a. Grinding 75% rhubarb, Coptis chinensis, Cortex Phellodendron, and Angelica dahurica into fine powder, sieved, and mixed;

[0036] b. Use 8 times the amount of 70% ethanol to percolate the remaining thick head, windproof, platycodon grandiflorum, and remaining rhubarb after being crushed and sieved in a, collect the filtrate, and reclaim ethanol;

[0037] c. Extract volatile oil from nepeta, mint and chuanxiong, and collect the distilled aqueous solution in another device;

[0038] d. Decoct the medicinal dregs in step c with Inula inulae, Forsythia, Gardenia, Scutellar...

Embodiment 3

[0040] Coptidis 24g Forsythia 240g Nepeta ear 240g Ginger gardenia 240g

[0041] 240 grams of Angelica dahurica, 480 grams of chrysanthemums, 144 grams of mint, 144 grams of fried cork with wine

[0042] Chuanxiong 144g Gypsum 144g Scutellaria baicalensis 144g Wine-roasted rhubarb 840g

[0043] Fangfeng 144g Platycodon grandiflorum 240g Inula 96g Fried vitex 240g

[0044] Licorice 144g

[0045] Its manufacturing method is:

[0046] a. Grinding 80% rhubarb, Coptis chinensis, Cortex Phellodendron and Angelica dahurica into fine powder, sieved and mixed;

[0047] b. Use 10 times the amount of 70% ethanol to percolate the remaining thick head and sieve after crushing in a, and the remaining rhubarb, platycodon grandiflorum, and collect the ethanol;

[0048] c. Extract volatile oil from nepeta, mint, and chuanxiong, and collect the distilled aqueous solution in another device;

[0049] d. Add water to decoct the medicinal residues in step c, Inula Inulae, Forsythia, Gardenia, ...

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Abstract

The invention relates to a goldthread root granule for heat-clearing, bowel relaxing, pain relieving, and the process for its preparation comprising boiling the raw material repeatedly, displacement for extraction. The invention realizes more complete extraction for effective composition and more complete removal of ineffective component, thus the curative effect for the product can be developed to the maximum limit.

Description

Technical field: [0001] The invention relates to a coptis shangqing granule for clearing heat and laxative, dispelling wind and relieving pain, and also relates to a preparation method thereof. Background technique: [0002] The existing Coptis chinensis supernatant product usually adopts the production step of crushing the drug and directly roughing it, the active ingredients cannot be fully extracted, and the drug effect is not good. [0003] purpose of invention [0004] The object of the present invention is to overcome above-mentioned deficiency, extract its active ingredient in a targeted manner, through a series of repeated refinement the Coptis chinensis supernatant granules and its manufacturing method. Contents of the invention [0005] In order to achieve the above object, the present invention adopts the following technical solutions: (by weight) [0006] Coptis 1-3 Forsythia 6-10 Nepeta ear 6-10 Ginger gardenia 6-10 [0007] Angelica dahurica 6-10 Chrysanth...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61P1/10A61P29/00
Inventor 向红
Owner 重庆东方药业股份有限公司
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