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Chinese traditional medicinal composition and its preparation process and usage

A technology for Chinese herbal medicine and composition, applied in the field of Chinese herbal medicine pharmaceutical composition and its preparation and use, can solve problems such as poor effect, and achieve the effects of reducing infiltration and necrosis, reducing and recovering proliferation of granulocyte progenitor cells, and improving SOD activity

Active Publication Date: 2005-03-16
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional drug therapy (mainly vasopressors) is ineffective, and the in-hospital mortality rate is still as high as 80% to 90% despite the combination of intra-aortic balloon counterpulsation

Method used

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  • Chinese traditional medicinal composition and its preparation process and usage
  • Chinese traditional medicinal composition and its preparation process and usage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1. A Chinese herbal medicinal composition, which is a medicament made of the following Chinese herbal raw materials by weight percentage,

[0033] Panax notoginseng 20% ​​Ginseng 20% ​​Ophiopogon japonicus 60%.

[0034] For the treatment of shock, viral myocarditis, chronic pulmonary heart disease, neutropenia.

Embodiment 2

[0035] Example 2. A Chinese herbal medicinal composition, which is a medicament made of the following Chinese herbal raw materials by weight percentage,

[0036] Panax notoginseng 10% Ginseng 10% Ophiopogon japonicus 80%.

[0037] For the treatment of shock, viral myocarditis, chronic pulmonary heart disease, neutropenia.

Embodiment 3

[0038] Example 3. A Chinese herbal medicinal composition, which is a granule made of the following Chinese herbal raw materials by weight percentage,

[0039] Notoginseng 15%, Ginseng 15%, Radix Ophiopogon 70%.

[0040] Its preparation method is,

[0041] (1) Ginseng, Ophiopogon japonicus and Notoginseng are crushed into coarse powder, refluxed with 5 times the amount of 60% ethanol and extracted twice for 2 hours each time, combined extracts, refrigerated for 24 hours, filtered, and the filtrate recovered Ethanol until there is no alcohol smell, refrigerate for 24 hours, and filter;

[0042] (2) the filtrate was extracted 5 times with water-saturated n-butanol in an equal amount, combined with n-butanol, recovered n-butanol under reduced pressure, and the residue was vacuum-dried to obtain dry extracts of Sanwei medicinal material extracts such as ginseng;

[0043] (3) Take the dry extract of the above-mentioned ginseng and other three medicinal material extracts, dry, grind...

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Abstract

The invention discloses a medicinal composition which is prepared from he following Chinese medicinal herbs (by weight ratio), notoginseng 10-30%, ginseng 10-10%, ophiopogon root 40-80%. The invention also discloses the process for preparing the pharmaceutical composition and use thereof.

Description

technical field [0001] The invention relates to a medicine made from Chinese herbal medicine, in particular to a Chinese herbal medicine composition. The invention also relates to the preparation method and medical application of the pharmaceutical composition. Background technique [0002] Viral myocarditis is one of the common cardiovascular diseases in pediatrics. Domestic and foreign studies have proved that oxygen free radical (reactive oxygen) damage plays an important role in the pathogenesis of viral myocarditis. At present, high-dose vitamin C antioxidant therapy is often used as the main treatment in clinical practice, but the curative effect is not exact. Therefore, it is of great significance to develop and develop drugs that can improve SOD activity in myocarditis, scavenge free radicals, improve pathological and ultrastructural changes, reduce inflammatory cell infiltration and necrosis, reduce mortality, and have definite cardioprotecti...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K9/20A61K9/48A61P7/00A61P9/02A61P11/00A61P31/12
Inventor 戴翔翎凌娅李明慧丁岗曹亮
Owner JIANGSU KANION PHARMA CO LTD
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