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Chinese medicinal preparation for treating arrhythmia and its preparation method

A traditional Chinese medicine preparation and arrhythmia technology, which is applied in the direction of medical formula, medical preparations containing active ingredients, pill delivery, etc. It can solve the problems of granules with peculiar smell, large dosage, and difficult taste for patients, so as to be easy to carry and take , process refining, high bioavailability effect

Active Publication Date: 2005-08-10
SHANDONG BUCHANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the actual clinical use process, it was found that: the granules have peculiar smell, and the taste is not easy for patients to accept; and some patients are unwilling to take the capsules and tablets of this product; The dose required by the dosage form is relatively large, and it is difficult for patients to take it; that is to say, the existing dosage form cannot fully meet the needs of both doctors and patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0089] Embodiment 1 of the present invention: get 30 parts of amber and pulverize into fine powder; 200 parts of Ganshen extract volatile oil, and the distilled aqueous solution is collected in another device; 300 parts, Radix Notoginseng medicinal residues and Gansong medicinal residues were decocted with water, combined the decoction liquid and the distilled aqueous solution of Gansong, filtered, the filtrate was concentrated into a clear paste, and alcohol precipitation was carried out twice to make the alcohol content respectively reach 75%, 80%, draw the supernatant, and merge with the notoginseng alcohol filtrate, reclaim the ethanol, concentrate under reduced pressure to a clear paste with a relative density of 1.30 (measured at 60°C), dry under reduced pressure, grind into fine powder, and The above amber fine powder is mixed evenly to obtain the extract fine powder, which is made into soft capsules according to the conventional method

Embodiment 2

[0090] Embodiment 2 of the present invention: get 70 parts of amber and pulverize into fine powder; 300 parts of Nardinus extract volatile oil, and the distilled aqueous solution is collected in another device; 100 parts of Panax notoginseng are extracted with ethanol reflux, and the filtrate is collected in another device; Add water to decoct 600 parts of Radix Notoginseng medicinal residues and Gansong medicinal residues, combine the decoction liquid and the distilled aqueous solution of Gansong pine, filter, concentrate the filtrate into a clear paste, carry out alcohol precipitation twice respectively, so that the alcohol content respectively reaches 60%, 90%, draw the supernatant, and merge with the notoginseng alcohol filtrate, reclaim the ethanol, concentrate under reduced pressure to a clear paste with a relative density of 1.35 (measured at 60°C), dry under reduced pressure, and be ground into fine powder. Mix the amber fine powder above to get the extract fine powder,...

Embodiment 3

[0091] Embodiment 3 of the present invention: 80 parts of amber are pulverized into fine powder; 100 parts of nard pine extract volatile oil, and the aqueous solution after distillation is collected in another device; 1 hour, filter, and combine the filtrate to collect in another device; add 150 parts of Codonopsis pilosula, 200 parts of Polygonatum, Radix Notoginseng and Gansong medicinal residues to decoct once for 3 hours, combine the decoction liquid and the distilled aqueous solution of Gansong, Filtrate, concentrate the filtrate to a clear paste with a relative density of about 1.10 (measured at 60°C), add ethanol under stirring to make the alcohol content reach 70%, let it stand, absorb the supernatant, reclaim the ethanol, and concentrate under reduced pressure to a relative density of about 1.30 (measured at 60°C) clear paste, ethanol precipitation again, add ethanol under stirring to make the alcohol content reach 75%, let it stand, absorb the supernatant, and combine...

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PUM

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Abstract

A Chinese medicine in the form of soft capsule or dripping pills for treating arrhythmia, palpitation, earhy heart beat is prepared from 5 Chinese-medicinal materials including pilose asiobell root, siberian solomonseal rhizome, notoginseng, amber, etc.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a traditional Chinese medicine preparation for treating arrhythmia and a preparation method thereof, belonging to the technical field of medicines. Background technique [0002] Arrhythmia is one of the common and frequently-occurring diseases of cardiovascular disease, which seriously endangers the health of people, especially the middle-aged and elderly people. Therefore, it has long been a hot topic that the medical community has focused on and devoted to research and solution. On April 9, 2003, the Chinese Patent Gazette published the patent application of "a traditional Chinese medicine for treating arrhythmia and its preparation method" declared by the applicant in the name of employee Comrade Yang Ximing, and the publication number is 1408389. It uses Codonopsis pilosula, sealwort, notoginseng, amber and nard pine as raw materia...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K9/48A61K35/10A61P9/06
Inventor 赵涛
Owner SHANDONG BUCHANG PHARMA
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