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Chuanhuang anti-inflammation drops for clearing away heat and detoxicating, and preparation thereof

A technology of anti-inflammatory dripping pills and pyrotoxins, which is applied to medical preparations containing active ingredients, pill delivery, and pharmaceutical formulations. Avoid gastrointestinal irritation symptoms, improve bioavailability, accelerate dissolution and absorption

Inactive Publication Date: 2005-10-12
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also pollute the environment. cause certain pollution
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0038] Now with several groups of specific examples, the preparation method of Chuanhuangxiaoyan dripping pills of the present invention will be further described.

[0039] Group 1: Tests with a single matrix

[0040] 1. According to [Appendix: A preparation method of a traditional Chinese medicine extract], take 375g of Andrographis paniculata and 625g of Solidago paniculata. 1.5 hours for the second time, combine the decoctions, filter, concentrate the filtrate to a clear paste with a relative density of 1.14-1.16 (85°C), let it cool, add ethanol until the alcohol content is 60%, stir, and stand for 48 hours, filtered, and the filtrate was concentrated to a thick paste with a relative density of 1.31 to 1.35 (60 to 80°C), then dried under low temperature and reduced pressure, and pulverized to obtain dry powder of the main drug for future use;

[0041] 2. Substrate: polyethylene glycol (1000~20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl ...

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PUM

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Abstract

A Chuanhuang Xiaoyan dripping pill based on the Chuanhuang xiaoyan tablet for treating acute upper respiratory tract infection, acute tonsillitis, and pharyngolaryngitis is disclosed. Its advantages are high release speed and quickly taking its high curative effect.

Description

technical field [0001] The present invention relates to a kind of medicinal composition with heat-clearing and detoxifying effect, which is used for the treatment of acute upper respiratory tract infection, acute tonsillitis, pharyngitis, etc. The oral drop pill preparation of a pharmaceutical composition reformed from the dosage form. Background technique [0002] According to the formula and extraction process given in the national drug standard WS-11053 (ZD-1053)-2002, Chuanhuang Xiaoyan Tablets is a kind of medicine with heat-clearing and detoxifying effects, which is used for acute upper respiratory tract infection and acute tonsillitis. Tablets for the treatment of diseases such as pharyngitis, pharyngitis and other diseases such as heat and toxin, have been clinically verified for many years, with stable quality and definite curative effect. They are commonly used pharmaceutical preparations for clinical and family treatment of the above diseases. [0003] The follow...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P11/00A61P11/04
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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