Pharmaceutical composition for preventing and curing endometritis and retained afterbirth disease of milk cow

A technology for endometritis and retained placenta, which is applied in the direction of drug combinations, active ingredients of iodine compounds, and active ingredients of artificially synthesized polymeric materials, etc., and can solve problems such as lack of data related to animal experiments, difficult inventions, and insufficient disclosure of patent applications , to achieve the effect of shortening the calving or calving interval, promoting the discharge of the placenta, and increasing the reproductive rate of the female animal

Inactive Publication Date: 2006-02-08
HUAZHONG AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there are some relevant reports on the prevention and treatment of dairy cow endometritis. For example, the Chinese invention patent application publication, the patent application number is 03142299.3. The preparation method, the preparation includes lysostaphin, lysozyme, bacteriostatic peptide, protein stabilizer, penetration enhancer and medically acceptable carrier, and the bacteriostatic test of relevant microorganisms has been carried out in vitr...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Prepare the actual addition of each component of the pharmaceutical composition of 1000kg milk cow endometritis and retained placenta prevention and treatment as follows:

[0040] Povidone-iodine 2kg

[0041] Potassium iodate 0.5kg

[0042] Propylene glycol 50kg

[0043] Oxytocin 6.77kg (purchased from Nanjing Animal Hormone Factory)

[0044] Carbomer 5kg (purchased from Beijing Guoren Yikang Technology Co., Ltd.)

[0045] Sodium hydroxide 5kg

[0046] Add water to 1000kg

[0047] The preparation steps are as follows: stir the carbomer with a little water to fully swell; add sodium hydroxide to make a gel matrix; then add povidone iodine and stir evenly; dissolve potassium iodate in a little water and add; finally add Add after mixing oxytocin and propylene glycol; add water to 1000kg and stir well.

Embodiment 2

[0049] Prepare the actual addition of each component of the pharmaceutical composition of 1000kg milk cow endometritis and retained placenta prevention and treatment as follows:

[0050] Povidone-iodine 10kg

[0051] Potassium iodate 5kg

[0052] Propylene glycol 100kg

[0053] Oxytocin 10.15kg (purchased from Nanjing Animal Hormone Factory)

[0054] Estrogen 5kg (purchased from Nanjing Animal Hormone Factory)

[0055] Carbomer 1kg (purchased from Beijing Guoren Yikang Technology Co., Ltd.)

[0056] Sodium hydroxide 2.2kg

[0057] Add water to 1000kg

[0058] The preparation steps are as follows: stir the carbomer with a little water to fully swell; add sodium hydroxide to make a gel matrix; then add povidone iodine and stir evenly; dissolve potassium iodate in a little water and add; finally add Add oxytocin, estrogen and propylene glycol after mixing; add water to 1000kg and stir well.

Embodiment 3

[0060] Prepare the actual addition of each component of the pharmaceutical composition of 1000kg milk cow endometritis and retained placenta prevention and treatment as follows:

[0061] Povidone-iodine 20kg

[0062] Potassium iodate 10kg

[0063] Glycerol 10kg

[0064] Oxytocin 0.677kg (purchased from Nanjing Animal Hormone Factory)

[0065] Carbomer 10kg (purchased from Beijing Guoren Yikang Technology Co., Ltd.)

[0066] Sodium hydroxide 10kg

[0067] Add water to 1000kg

[0068] The preparation steps are as follows: stir the carbomer with a little water to fully swell; add sodium hydroxide to make a gel matrix; then add povidone iodine and stir evenly; dissolve potassium iodate in a little water and add; finally add Add after mixing oxytocin and glycerin; add water to 1000kg and stir well.

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PUM

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Abstract

The invention discloses a combined medicinal composition for the prevention and treatment of cow's endometritis, the preparation process and use, wherein the medicinal composition comprises right amount of Povidone iodine, potassium iodate, propylene glycol or glycerin, oxytocin, estrogen, carbomer, sodium hydroxide and water.

Description

technical field [0001] The invention belongs to the technical field of preparation of veterinary drugs, and in particular relates to a combined drug for preventing and treating dairy cow endometritis and retained placenta and its preparation method and application. The drug is mainly used for the prevention of dairy cow endometritis and retained placenta and treatment to increase the reproductive rate of dairy cows. Background technique [0002] Dairy cow endometritis is a common multiple disease in the dairy cattle breeding industry, and the incidence rate is generally more than 30%. Bacterial contamination of the uterus at 2 weeks postpartum is extremely common. In the early postpartum period, as many as 93% of dairy cows develop varying degrees of intrauterine bacterial infection (Elliott, L., McMahon, K.J., Gier, H.T. and Marion, G.B. 1968). Endometritis will not only lead to long-term infertility in some dairy cows or low conception rat...

Claims

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Application Information

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IPC IPC(8): A61K38/11A61K33/18A61P15/00A61K31/80A61K38/095
Inventor 杨利国莫莉
Owner HUAZHONG AGRI UNIV
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