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Method and apparatus for using optical tweezers to manipulate materials

A technology of equipment and light beams, applied in the direction of biochemical equipment and methods, special-purpose bioreactors/fermenters, optics, etc.

Inactive Publication Date: 2006-04-26
UNIVERSITY OF CHICAGO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0008] In special cases, however, laser-induced damage may be desirable

Method used

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  • Method and apparatus for using optical tweezers to manipulate materials
  • Method and apparatus for using optical tweezers to manipulate materials
  • Method and apparatus for using optical tweezers to manipulate materials

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Embodiment Construction

[0032] In order to better understand the improvement of the present invention, figure 1 and 2 Several methods and systems of the prior art are described. exist figure 1 In the optical tweezer system 10 of , the optical gradient force is generated due to the controllable manipulation of small dielectric particles 14 dispersed in a medium 16 using a single beam 12, wherein the medium has a refractive index n m smaller than the refractive index of the particle 14. The fundamental properties of optical gradient forces are well known, and of course in general terms the principle can manipulate reflection, absorption and low dielectric constant particles. Any of these techniques may be implemented in the description of the improvements of the invention described below, and the terms optical clamp, optical trap and optical gradient force trap will be used for description hereinafter.

[0033] The optical clamp system 10 is applied by using a light beam 12, such as a laser beam or...

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Abstract

An optical system for manipulating biological material without substantial damage to the biological material, the optical system including a source for a laser beam, optics for manipulating the laser beam to form an optical trap, the optical system characterized in that the laser beam has a light wavelength less than infrared light such that the biological material has a weak absorption coefficient for the light wavelength, and the optical trap comprised of an arrangement of optical traps distributed over the biological material to spread power P from the laser beam over a plurality of locations, N, thereby reducing power at each location by P / N.

Description

[0001] This application is a divisional application of a patent application with an application date of October 7, 2003, an application number of 02808941.3 (PCT / US 02 / 13307), and a title entitled "Equipment for Manipulating Materials Using Optical Tweezers". [0002] This work was made with the support of the U.S. Government through a GAANN Fellowship from the Department of Education under Contract No. DMR-9730189 to the National Science Foundation under Contract No. invention. The US Government also has certain rights in this invention. technical field [0003] In general the present invention relates to methods and apparatus for controlling an optical trap or optical tweezer. More specifically, the present invention relates to optical tweezers formed using visible light that can be used to manipulate a variety of light-sensitive materials, such as living biological materials, without causing significant damage or deleterious effects to the material being studied or manipul...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G02B21/32G02B27/42C12M1/00C12N1/00
CPCG02B21/32G02B27/1086G02B27/42G02B27/4244G02B27/425
Inventor 戴维·G·格里尔埃里克·R·迪弗雷纳詹妮弗·E·库尔蒂斯布赖恩·A·考斯
Owner UNIVERSITY OF CHICAGO
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