Production process of water soluble ginkgo leaf extract

A production method and technology of ginkgo biloba, applied in the processing field of ginkgo biloba extract, can solve the problems that it is difficult to eliminate the harmful effects of resin residues, cannot meet the requirements of raw materials, and cannot solve the problems of water solubility at the same time, so as to achieve non-toxic and low-cost products. The effect of low and stable product quality

Inactive Publication Date: 2006-05-17
何照范
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These applications all belong to the method of extracting general GBE from ginkgo leaves. Only the patent application No. 02113533.9 "Production process of water-soluble ginkgo leaf extract" is used to extract water-soluble GBE. This process uses a macroporous adsorption resin process, and it is difficult to eliminate resin residu

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] The first step, feeding: take 20kg of GBE crude product;

[0014] The second step, extraction: add 200L of pure water to the crude product, stir and extract at 25°C for 1.5 hours, let stand for 2 hours, and filter;

[0015] The third step, precipitation: add 5% gelatin aqueous solution to the filtrate, stir clockwise until no white precipitate (white turbidity) appears, continue to stir for about 10 minutes, then let stand for 13 hours, filter, and concentrate in vacuo to dry;

[0016] The fourth step, dissolving: add 6 times of absolute ethanol to the dry matter by weight, stir to dissolve completely, and filter;

[0017] The fifth step, concentration: put the filtrate into a vacuum concentrator and concentrate it to a slurry;

[0018] In the sixth step, the material is dried with hot air under vacuum, and finally crushed to obtain the fifth-generation GBE of ginkgo biloba.

Embodiment 2

[0020] The first step, feeding: take 50kg of GBE crude product;

[0021] The second step, extraction: add 500L of dilute ethanol solution with a mass fraction of 20% to the crude GBE, stir and extract at 40°C for 1.5 hours, let stand for 1 hour, and filter;

[0022] The third step is filtration: the filtrate is first filtered through the ceramic membrane, and then enters the 2000-10000 molecular weight ultrafiltration device system for ultrafiltration;

[0023] The fourth step, concentration: pour the ultrafiltrate into a vacuum concentrator to concentrate to a slurry;

[0024] In the fifth step, the material is dried with hot air under vacuum, and finally crushed to obtain the fifth-generation GBE of ginkgo biloba.

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PUM

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Abstract

The present invention is production process of water soluble ginkgo leaf extract. Ginkgo leaf GBE coarse product as material is produced into the generation-V GBE through extraction with pure water or solvent in a lixiviation apparatus, letting stand, filtering, precipitating with water solution of gelatin, filtering, filtering, vacuum concentrating to dry, dissolving in anhydrous alcohol, filtering, vacuum concentrating, drying and crushing. The production process is simple, high and stable in product quality and low in product cost, and produces no toxic matter and waste, and the product is non-toxic, reliable, high in quality and high in water solubility.

Description

technical field [0001] The present invention relates to the processing method of Ginkgo biloba extract (abbreviated as GBE), in particular to the method of producing water-soluble extract from the crude product of Ginkgo biloba extract. Background technique [0002] Ginkgo biloba, also known as ginkgo leaf, is the leaf of Ginkgo biloba (Ginkgo biloba), which is bitter in taste and flat in nature. It is used as medicine because it contains flavonoid glycosides and terpene lactones. effect. In recent years, people continue to study the medicinal value and extraction method of extracting Ginkgo biloba leaves. At present, there are many methods for extracting Ginkgo biloba GBE, and many new processes have applied for invention patents. By searching, there are 25 patent applications related to Ginkgo biloba extraction, such as No. CN02134490.6 "Preparation of a kind of Ginkgo biloba extract Method", CN02129905.6 "a preparation and application of high-activity ginkgo leaf extrac...

Claims

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Application Information

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IPC IPC(8): A61K36/16
Inventor 何照范何珺
Owner 何照范
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