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Sustained release capsules of ginkgo leaf and prepn. method

A technology of sustained-release capsules and ginkgo leaves, which is applied in the directions of capsule delivery, medical raw materials derived from Ginkgo biloba, antidote, etc., can solve the problems of easy leakage and inconvenience in taking, and achieves convenient taking, reduced toxic and side effects, and increased compliance. Effect

Active Publication Date: 2006-09-20
黑龙江澳利达奈德制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Ginkgo biloba capsules and tablets need to be taken three times a day, one capsule at a time, and other similar transplant products also need to be taken three times a day, and most patients with cardiovascular and cerebrovascular diseases are elderly, which is inconvenient to take and easy to miss. The market demand for long-acting sustained-release dosage forms is urgent and the market capacity is huge

Method used

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  • Sustained release capsules of ginkgo leaf and prepn. method
  • Sustained release capsules of ginkgo leaf and prepn. method
  • Sustained release capsules of ginkgo leaf and prepn. method

Examples

Experimental program
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Embodiment 1

[0029] Get 200g povidone K30, 200g dewaxed bleached shellac and 200g isopropanol, and mix and stir them uniformly for later use. In addition, take ginkgo biloba extract, talcum powder, and some blank ball cores, which can be appropriately excessive.

[0030] Spray the prepared isopropanol mixed solution onto the blank ball core with a spray gun, and then gradually sprinkle the ginkgo leaf extract until the surface of the ball core is evenly sprinkled with a layer; repeat the spraying until all the ginkgo leaf extract is added; Then sieve and dry to prepare ginkgo biloba extract pellets.

[0031] Put the ginkgo leaf extract pellets into the coating pan, spray the prepared isopropanol mixed solution onto the pellets with a spray gun, and then gradually sprinkle talcum powder until the surface of the pellets is uniformly sprinkled. Repeated spraying until all the mixed solution of isopropanol is sprayed; then sieved, dried, lubricated with talcum powder and then filled into caps...

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Abstract

A slowly-releasing gingko leaf capsule is prepared through preparing the solution of polyvitone K30 and dewaxed and bleached lac in isopropanol, carrying the extract of gingko leaf, and coating.

Description

technical field [0001] The invention relates to a ginkgo leaf extract medicine and a preparation method thereof. technical background [0002] At present, there are more than 30 kinds of ginkgo products in the world, and relevant experts believe that the annual sales of ginkgo preparations in the world are 2 to 4 billion US dollars. Since the 1980s, Ginkgo biloba extract has become the focus of research and development in the pharmaceutical industry. Ginkgo biloba extract is listed as an important medicine for treating cardiovascular and cerebrovascular diseases, dementia and anti-aging. [0003] However, the present ginkgo leaf preparation has problems such as single preparation, large dosage, many times of taking, poor patient compliance, etc., which greatly affects the clinical curative effect of the medicine. At present, there are ginkgo biloba oral liquid, capsules, tablets, etc. in China. Ginkgo biloba capsules and tablets need to be taken three times a day, one cap...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/16A61K9/48A61P9/00A61P25/28A61P39/06
Inventor 周有财
Owner 黑龙江澳利达奈德制药有限公司