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Application of ocotillol type ginsenoside and its glucoside

A technology of octilonol and saponin, which is applied in the field of medicine and can solve the problems of short action time and reduced action

Inactive Publication Date: 2006-12-13
FUDAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Caffeine is one of the most commonly used "refreshing" drugs. Its main disadvantage is that its action time is short, and its effect will be greatly reduced after repeated use.

Method used

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  • Application of ocotillol type ginsenoside and its glucoside
  • Application of ocotillol type ginsenoside and its glucoside

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Embodiment 1: Preparation of ginsenoside F11 aglycon tablet, capsule and injection:

[0052] (1) Tablet prescription (1000 tablets):

[0053] Ginsenoside F11 Aglycone 200g

[0054] Microcrystalline Cellulose 40-60g

[0055] Carboxymethyl starch 20-30g

[0056] Magnesium Stearate Appropriate amount

[0057] Lactose 45-55g

[0058] Prepared by usual techniques.

[0059] (2) Capsule prescription (1000 capsules):

[0060] Ginsenoside F11 Aglycone 200g

[0061] Magnesium Stearate Appropriate amount

[0062] Lactose 25-40g

[0063] Prepared by usual techniques.

[0064] (3) Injection prescription (2ml each, containing 0.4g of F11 aglycone):

[0065] Ginsenoside F11 Aglycone 200g

[0066] Tween 80 25-50g

[0067] Propylene glycol 60-120ml

[0068] Add water for injection to 1000ml

[0069] Prepared by usual techniques.

Embodiment 2

[0070] Embodiment 2: Preparation of infarctin-R2 tablet, capsule and chewable tablet

[0071] (1) Tablet prescription (1000 tablets):

[0072] Infarctin-R2 200g

[0073] Dextrin 20-60g

[0074] Appropriate amount of dextrin starch slurry

[0075] Magnesium Stearate Appropriate amount

[0076] Prepared by usual techniques.

[0077] (2) Capsule prescription (1000 capsules):

[0078] Infarctin-R2 200g

[0079] Magnesium Stearate Appropriate amount

[0080] Lactose 25-40g

[0081] Prepared by usual techniques.

[0082] (3) Prescription for chewable tablets (1000 tablets):

[0083] Infarctin-R2 500g

[0084] Mannitol 150-300mg

[0085] Powdered sugar 80-200mg

[0086] Appropriate amount of starch

[0087] 5% PEG6000 appropriate amount

[0088] Magnesium Stearate Appropriate amount

[0089] Prepared by usual techniques.

[0090] The above-mentioned various preparations can be used as medicines for treating and alleviating symptoms such as attention deficit disorder, ...

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Abstract

The invention relates the gen-seng ocotillo spooning and glycoside. The gen-seng ocotillo spooning and glycoside has good central stimulating action, so it can be used to prepare mental stimulant, health products, food additives and compound recipe preparation. It is mainly used to cure paroxysmal sleep and depression. It also can be used to cure proscenia, recover fatigue, improve memory, and modify emotion.

Description

technical field [0001] The invention belongs to the technical field of medicine, and specifically relates to a use of ginseng octilol-type sapogenin and its glycoside as a pharmacological action based on the central excitatory action and a medicine or health care product prepared therefrom. Background technique [0002] Central stimulant drugs can excite the central nervous system and improve its functional activities, promote the recovery of brain function, and have dual purposes of clinical and daily life. [0003] Ginsenosides contain a variety of chemical components with different or even opposite activities, so it is necessary to conduct detailed and in-depth studies on individual components in ginseng. It has been reported at home and abroad that total saponins of ginseng have a two-way regulation effect on the nervous system. The possible reason for this is that ginseng contains chemical components with opposite effects. After screening, it was found that the compoun...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/58A61K31/7048A61K9/20A61K9/48A61K9/08A61K9/19A61K9/107A61K9/70A61P25/26
Inventor 王泽君王泽梅
Owner FUDAN UNIV
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